左西孟坦治疗老年重度心力衰竭的临床价值分析  

Clinical Value Analysis of Levosimendan in the Treatment of Elderly Patients with Severe Heart Failure

作　　者：孔令武 

机构地区：[1]蒲城县县医院,陕西蒲城715500

出　　处：《现代诊断与治疗》2013年第8期1695-1697,共3页Modern Diagnosis and Treatment

摘　　要：目的观察左西孟坦治疗老年重度心力衰竭的疗效及临床应用价值。方法将老年重度心力衰竭患者80例随机均分为观察组与对照组。两组均予以常规治疗,对照组予以静脉维持泵注5ug/(kg.min)的多巴酚丁胺,持续24h;观察组予以静注左西孟坦,初始负荷量为12ug/kg,10min后静注0.1ug/(kg.min),然后静脉滴注0.25～1.0ug/(kg.min)。结果观察组的治疗总有效率明显较对照组更高(P<0.05),治疗2w以后,观察组各项指标较对照组改善更为明显(P<0.05)。结论左西孟坦治疗老年重度心力衰竭具有较好的临床疗效,安全可靠,患者的耐受性较好,值得临床推广应用。Objective To analysis efficacy and clinical application value of levosimendan in the treatment of elderly patients with severe heart failure. Methods A total of 80 elderly patients with severe heart fail-ure, randomly divided into observation group and control group. The two groups are to be the conventional treatment, the control group, to be intravenous maintain infusion 5ug/（ kg ~ min） of dobutamine, continu- ous 24h; observation group was treated with intravenous levosimendan initial load 12ug/kg, 10min after intravenous 0.1 ug/（ kg. min）, then intravenous infusion of 0.25 - 1.0 ug/（ kg .rain）. Results The total effective rate of the observation group was significantly higher than the control group （ P 〈 0.05 ）, af- ter two weeks of treatment, the indicators of the observation group than in the control group improved more significantly （P 〈 0.05 ）. Conclusion Levosimendan better clinical efficacy for the treatment of elderly patients with severe heart failure, safe, reliable, and better tolerated by patients, worthy of promotion in clinical application.

关 键 词：心力衰竭 老年患者 左西孟坦 临床疗效 价值 

分 类 号：R541.61[医药卫生—心血管疾病]