分子筛负载磷钨酸盐催化合成2-乙酰噻吩的研究  

The study on catalytic synthesis 2-acetyl thiophene with moecular sieve load phosphorus tungstate

作　　者：郭海峰 郝丽君 

机构地区：[1]山西侨友化工股份有限公司,山西忻州034000

出　　处：《山西化工》2013年第4期15-17,共3页Shanxi Chemical Industry

摘　　要：采用二氧化硅负载固体磷钨酸盐催化剂，以乙酸酐和噻吩为原料合成2-乙酰噻吩。通过实验考察了固体酸盐催化剂用量、反应时间、反应温度、催化剂重复使用次数对2-乙酰噻吩合成转化率的影响。确定该反应的最适条件为：反应温度85℃，反应时间4h，催化剂用量（质量分数）3．0％-3．5％，催化剂重复使用3次。产品的转化率为80％以上，最高转化率达到90．75％。产品通过气相色谱分析，2．乙酰噻吩质量分数达99．5％以上，副产物主要为3-乙酰噻吩。由此证明，磷钨酸盐作为本反应的催化剂，有着较高的选择性。该方法同以往的方法相比较，具有无设备腐蚀、减少环境污染等优势。产品同催化剂易分离，且催化剂可重复利用。Using silica attached solid phosphorus tungstate catalyst, with acetic anhydride and thiopene as raw material to synthesize 2- acetyl thiophene. Through experimental investigation salt soild acid catalyst, the reaction time, reaction temperature, catalyst reuse fre- quency conversion rate for 2-aeetyl thiophene synthesis. Determine the optimal conditions for the reaction temperature is 85 ℃, reac- tion time is 4 hours, 3.0-3.5 % （w/w） of catalyst, catalyst reuse 3 times as the best reaction conditions. The conversion rate of more than 80% of the product, the highest conversion rate 90.75%. Products from the taiyuan university of science and technology of mete- orological chromatography analysis, 2-acetyl thiophene mass fraction of more than 99.5%, by-products are mainly 3-acetyl thiopene. It also proved that phosphotungstic acid salt as the reaction catalyst, has a higher selectivity, this method is compared with the past, we have no equipment corrosion, reduce environmental pollution and other advantages. Products with catalyst easy separation, and the cat- alyst can be reused.

关 键 词：磷钨酸铝 2-乙酰噻吩 噻吩 乙酸酐 二氧化硅分子筛 合成 

分 类 号：TQ03[化学工程] O626.12[理学—有机化学]