Synthesis of Toluene-2,4-Bisurea from 2,4-Toluene Diamine and Urea and the Reaction Kinetics  

作　　者：王娜 耿艳楼 安华良 赵新强 王延吉 

机构地区：[1]Hebei Provincial Key Lab of Green Chemical Technology & High Efficient Energy Saving, Hebei University of Technology

出　　处：《Chinese Journal of Chemical Engineering》2013年第8期927-932,共6页中国化学工程学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China （20976035, 21076059）; the Natural Science Foundation of Hebei Province （B2010000019）

摘　　要：Toluene-2,4-bisurea (TBU) is an important intermediate for urea route to dimethyl toluene-2,4-dicarbamate and the study on TBU synthesis via the reaction of 2,4-toluene diamine (TDA) and urea is of great significance. Firstly, thermodynamic analysis shows that the reaction is exothermic and a high equilibrium conversion of TDA is expected due to its large reaction equilibrium constant. Secondly, under the suitable reaction conditions, 130 °C, 7 h, and molar ratio of TDA/zinc acetate/urea/sulfolane 1/0.05/3.5/10, TDA conversion is 54.3%, and TBU yield and selectivity are 39.8% and 73.3% respectively. Lastly, the synthesis of TBU is a 1st order reaction with respect to TDA and the reaction kinetics model is established. This work will provide useful information for commercializing the urea route to toluene-2,4-dicarbamate (TDC).Toluene-2,4-bisurea （TBU） is an important intermediate for urea route to dimethyl toluene-2,4-dicarbamate and the study on TBU synthesis via the reaction of 2,4-toluene diamine （TDA） and urea is of great significance. Firstly, thermodynamic analysis shows that the reaction is exothermic and a high equilibrium conversion of TDA is expected due to its large reaction equilibrium constant. Secondly, under the suitable reaction conditions, 130 °C, 7 h, and molar ratio of TDA/zinc acetate/urea/sulfolane 1/0.05/3.5/10, TDA conversion is 54.3%, and TBU yield and selectivity are 39.8% and 73.3% respectively. Lastly, the synthesis of TBU is a 1st order reaction with respect to TDA and the reaction kinetics model is established. This work will provide useful information for commercializing the urea route to toluene-2,4-dicarbamate （TDC）.

关 键 词：2 4-toluene diamine UREA toluene-2 4-bisurea reaction kinetics 

分 类 号：TQ246.31[化学工程—有机化工] O643.1[理学—物理化学]