Synthesis and Biological Activities of Novel Anthranilic Diamides Analogues Containing Benzo[b]thiophene  

作　　者：ZHANG Ji-feng LIU Chen LIU Peng-fei YAN Tao WANG Bao-lei XIONG Li-xia LI Zheng-ming 

机构地区：[1]State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P.. R. China

出　　处：《Chemical Research in Chinese Universities》2013年第4期714-720,共7页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China（No.20872069）, the National Basic Research Program of China（No.2010CB 126106）, the National Key Technologies R＆D Program of China（No.2011BAE06B05）, the Tianjin Natural Science Foundation, China（No. 11JCYBJC08600） and the Fund of State Key Laboratory of Elemento-Organic Chemistry, China.

摘　　要：A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, 1H nuclear magnetic resonance（IH NMR） and high-resolution mass spectrometry（HRMS）. The bioassay tests indicate that their insecticidal activities were weak to moderate. Antibacterial tests indicate that some of the compounds showed favourable activity in vitro against Physa- lospora piricola, Alternaria solani, Cercospora arachidicola, Gibberella sanbinetti and Phytophthora infestans at a dosage of 50 mg/L.A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, 1H nuclear magnetic resonance（IH NMR） and high-resolution mass spectrometry（HRMS）. The bioassay tests indicate that their insecticidal activities were weak to moderate. Antibacterial tests indicate that some of the compounds showed favourable activity in vitro against Physa- lospora piricola, Alternaria solani, Cercospora arachidicola, Gibberella sanbinetti and Phytophthora infestans at a dosage of 50 mg/L.

关 键 词：Anthranilic diamide Benzo[b]thiophene Insecticidal activity Antibacterial activity 

分 类 号：S482.39[农业科学—农药学] TQ225.261[农业科学—植物保护]