滋养血管在下肢静脉曲张管壁病理学变化的研究  

Pathologic Change Study of Vasa Vasorum in Vessel Wall of Varicose Vein of Lower Extremity

作　　者：王国华[1] 李凤臣[1] 徐兵[1] 陈智年[1] 魏定夏[1] 

机构地区：[1]新乡市中心医院血管外科,河南新乡453000

出　　处：《中国普外基础与临床杂志》2013年第8期919-921,共3页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探讨下肢静脉曲张血管壁中滋养血管的变化。方法收集32例(36条)下肢静脉曲张管壁标本。对12例(16条)曲张静脉(曲张组)、9例下肢静脉曲张复发(复发组)、11例下肢血栓性浅静脉炎(静脉炎组)、9例正常静脉(对照组)行HE染色,观察滋养血管分布并测定滋养血管密度。结果曲张组、复发组、静脉炎组外膜和中膜层可见滋养血管明显增多,而内膜少见。曲张组、复发组、静脉炎组滋养血管密度(个/mm2)分别为5.65±1.45、6.20±1.73、5.94±1.63,均明显大于对照组(2.87±0.54),差异有统计学意义(P<0.05);曲张组、复发组、静脉炎组3组间滋养血管密度比较差异均无统计学意义(P>0.05)。结论滋养血管的变化可能是下肢静脉曲张发病机制的一个重要病理改变。Objective To investigate the change of vasa vasorum in vessel wall of varicose vein of the lower extremity.Methods Thirty-two patients with varicose vein of the lower extremity were collected,in which of 12 patients with simple varicose veins（varicose group）,9 patients with recurrent varicose veins（recurrent group）,11 patients with thrombophlebitis of varicose vein（thrombophlebitis group）,9 patients with normal venous tissue as control group.HE staining was performed to observe the distribution of vasa vasorum and detect the vasa vasorum density.Results The increasing vasa vasorums were observed in the adventitia and media,but few was observed in the intima in the varicose,recurrent,and thrombophlebitis groups.The distribution of vasa vasorum was in the adventitia in the control group.The vasa vasorum densities（/mm2）in the varicose,recurrent,and thrombophlebitis groups（5.65±1.45,6.20± 1.73,and 5.94±1.63,respectively）were greater than those in the control group（2.87±0.54）,the difference was statistically significant（P0.05）,but there was no significant difference of the vasa vasorum density among the varicose vein,recurrent,and thrombophlebitis groups（P0.05）.Conclusion Change of vasa vasorum is an important patholgical change with the nosogenis of varicose vein of the lower extremity.

关 键 词：静脉曲张 滋养血管 血管重塑 密度 

分 类 号：R654.4[医药卫生—外科学]