基于FLUKA平台的重离子治癌模拟实验  

Heavy-ion cancer therapy with the FLUKA Monte-Carlo simulations

作　　者：薛万冬 李鹏程[1] 喻晓[1] 孙保华[1] 杜广华[2] 

机构地区：[1]北京航空航天大学软件开发环境国家重点实验室和物理科学与核能工程学院,北京100191 [2]中国科学院近代物理研究所,甘肃兰州730000

出　　处：《大学物理》2013年第7期47-50,60,共5页College Physics

基　　金：软件开发环境国家重点实验室自主研究课题(SKLSDE-2011ZX-18);新世纪优秀人才支持计划(NCET-09-0031);国家自然科学基金(10975008;11105010;11035007;11128510)资助

摘　　要：重离子治癌是指利用大型重离子加速器产生的高能带电重离子束辐照病灶来治疗恶性肿瘤的一种新型放射治疗方法.与传统的常规放射治疗方法相比,重离子束治疗癌症具有特殊的布拉格峰和高RBE优势.相关研究目前已成为放射治疗领域的前沿和热点,同时作为核科学前沿也常被引入到相关专业教学中,由于使用大型重离子加速器的实验教学很难引入高校,为了更好地展示加速器在核医学实验和临床治疗中的使用过程和效果,本文利用FLUKA软件作为操作平台,模拟了用碳离子束治疗脑部肿瘤的实验过程,并根据模拟结果调节参数,给出优化的治疗方案,使学生更深刻的掌握重离子与物质相互作用过程以及重离子治癌的基本原理.The Heavy-ion cancer therapy, as a new radiotherapy approach, cures malignant tumours by irradi- ating tumours with high-energy charged heavy-ion beams produced by large-scale heavy-ion accelerators. In com- parison with traditional and conventional radiotherapies, the heavy-ion therapy has a unique Bragg peak as well as high relative biological effectiveness（RBE） , thus it has attracted lots of attentions and has been one of the frontiers in radiotherapies. Meanwhile, as a highlight of nuclear technologies, the heavy-ion therapy has often been intro- duced into the relevant training programs. Due to the need of large-scale heavy-ion accelerators, however, it is hard to have such educational experiments in college. Here we report a virtual experiment for demonstrating the general concept of heavy-ion therapy with the FLUKA Monte-Carlo simulations. In this experiment, it is possible to simulate the whole process of carbon ion radiotherapy, from optimizing the heavy-ion beam to finalizing the best treatment. This experiment is demonstrated to be very helpful for students to understand the interaction of heavy ion with matter and the principle of heavy-ion therapy.

关 键 词：重离子与物质相互作用 重离子治癌 蒙特卡罗模拟 

分 类 号：O571[理学—粒子物理与原子核物理]