微生态制剂Sylvam exam治疗婴幼儿轮状病毒肠炎的临床研究  

CLINICAL EVALUATION OF EFFECTS OF MICROECOLOGICAL PREPARATION SYLVAMEXAM ON ROTAVIRUS DIARRHEA IN CHILDREN

作　　者：王树山[1] 马煜[1] 张宝元[1] 邓莉[1] 周欣[1] 宋文红[1] 刘丽 张丽娥 王月香[1] 

机构地区：[1]首都儿科研究所,北京100020

出　　处：《中国微生态学杂志》1999年第6期361-363,共3页Chinese Journal of Microecology

摘　　要：目的:为评估Sylvam exam 治疗婴幼儿急性腹泻的疗效。方法:在小儿轮状病毒腹泻流行期间,选择该病住院患儿,分为Sylvam exam 及乳酶生两组各 30 例进行对比研究。两组的性别、年龄、病情相似。两组都做了HRV-RNA 病毒检测(PAGE 法),阳性率分别为76.67% 和83.33% ,无显著性差异(P> 0.05)。结果:Sylvam exam (治疗组)与乳酶生(对照组)总有效率为86.67% 和53.33% (P< 0.05),治疗组优于对照组。在HRV- RNA 阳性的病例中:治疗组为23 例,对照组为25 例,其总有效率分别为86.96% 和52.00% ,治疗组也优于对照组(P< 0.05)。两组治疗后的止泻平均时间分别为3±1.34 天和4.27±0.89 天,治疗组也优于对照组(P< 0.05)。结论:Sylvam examObjective In order to evaluate the effects of microecological preparation Sylvamexam on rotavirus diarrhea in children,30 hospoitalized child cases of rotavirus diarrhea during an epidemic of rotavirus infection were treated with Sylvamexam. Methods 30 cases were treated with the tradtional Lactasine as a control group. All clinical conditions were similar in both groups. Rotavirus detection was done by PAGE method, detection rates were 76.67% and 83.33% for both groups (P>0.05). Results total effective rates were higher in the Sylvamexam group than control group (respectively 86.67% and 53.33%). The total effective rates were 86.96% in 23 HRV-RNA positive Sylvamexam cases and 52.00% in 25 HRV-RNA positive control cases (P<0.05). The times of loose stool stop were 3±1.34 days and 4.27±0.89 days (P<0.05). Conclusion The effect of Sylvamexam on childern's infections diarrhea may be better than that of Lactasine.

关 键 词：Sylvamexam 乳酶生 轮状病毒肠炎 婴幼儿 

分 类 号：R725.705[医药卫生—儿科]