体检人群随访两年心血管及代谢指标异常检出率变化分析  

Identification of abnormal cardiovascular and metabolic parameters in healthcare check-uppopulations during two years＇ follow-up

作　　者：刘琳[1] 武留信[1] 强东昌[1] 高向阳 师绿江[1] 王致洁[1] 姜媛媛[1] 

机构地区：[1]解放军空军航空医学研究所,北京100142 [2]中国健康促进基金会健康管理研究所

出　　处：《中华健康管理学杂志》2013年第4期239-241,共3页Chinese Journal of Health Management

基　　金：国家“十一五”支撑计划项目资助（2008BA152802）

摘　　要：目的探讨体检人群心血管及代谢指标的异常检出率变化，为心血管及代谢性疾病的早期筛查及健康干预提供依据。方法采用回顾性队列研究，收集北京某体检机构2008年度与2010年度5578名人群的体检数据（男性3404名，占61．0％，女性2174名，占39．0％），从中选取2008年、2010年均在该机构体检的人群作为本研究的研究对象，分析该人群随访两年后的血压、血脂、空腹血糖指标异常检出率变化情况。描述采用配对t检验和配对秩和检验等统计学方法。结果随访两年后血压异常检出率的比例下降，而血糖、总胆固醇、低密度脂蛋白胆固醇升高，差异均有统计学意义（t=5．378、13．885、3．210、10．401、4．355，P〈0．05）；高密度脂蛋白胆固醇和三酰甘油的异常检出率差异无统计学意义（t=1．204、-0．012，P〉0．05）。结论心血管及代谢指标异常检出率随时间呈动态变化特点，掌握动态变化的规律，并采取有效干预措施，能够降低心血管等疾病的发生风险。Objective To investigate the detection rate of abnormal cardiovascular and metabolic indicators in health check-up popuiations, and provide evidence for early screening and health interventions for cardiovascular and metabolic diseases. Methods A total of 5578 adults （male 3404 and female 2174） were recruited from a medical institution in Beijing in 2008 and 2010. Cardiovascular and metabolic indicators,including blood pressure, lipid profile and fasting plasma glucose, were tested at baseline and 2 years. Paired t test or paired rank sum test was used for data analysis. Results Detection rate of abnormal blood pressure in 2010 was lower than that in 2008; however, rates of abnormal total cholesterol, low-density lipoprotein cholesterol and fasting plasma glucose were higher in 2010 than in 2008 （t values were 5. 378, 13. 885,3. 210,10. 401 and 4. 355, respectively; all P 〈 0.05 ）. High-density lipoprotein cholesterol and triglyceride showed no statistically significant difference between 2008 and 2010 （ t values were 1. 204 and -0. 012,respectively; both P 〉 0. 05）. Conclusion We have been observing a dynamic change in abnormal cardiovascular and metabolic indicators, based on which effective interventions could be taken to reduce the risk of cardiovascular diseases.

关 键 词：体格检查 心血管疾病 随访研究 健康体检 

分 类 号：R194.3[医药卫生—卫生事业管理]