三种小鼠血液生理生化正常值的测定  

Determination of Hematological and Biochemical Parameters in Three Stocks of Mice

作　　者：王冬平[1] 李善如[1] 张敏[2] 李升团[2] 郑亚萍[1] 耿志贤[1] 李润芳 

机构地区：[1]军事医学科学院实验动物中心,北京100071 [2]军事医学科学院微生物流行病学研究所,北京100071

出　　处：《实验动物科学与管理》2000年第2期24-28,共5页Laboratory Animal Science & Administration

摘　　要：本文通过对三种小鼠—BALB/c、C57BL/6J近交系小鼠和昆明远交群小鼠的血液学和血液生化指标进行测定。其结果 :(1 )血液学指标 :BALB/c近交系小鼠的嗜中性白细胞、淋巴细胞雌雄间差异显著 ;C57BL/6J近交系小鼠、昆明小鼠雌雄间差异不显著 ;昆明小鼠的白细胞比BALB/c、C57BL/6J近交系小鼠的低 ;BALB/c近交系小鼠的单核细胞、嗜酸性白细胞、嗜碱性白细胞记数比C57BL/6J近交系小鼠和昆明小鼠的低。 (2 )血液生化指标 :C57BL/6J近交系小鼠的CHO ,Tbili,ALT ,AST值高于BALB/c和昆明小鼠 ,而昆明小鼠的C1值低于BALB/c和C57BL/6J近交系小鼠。BALB/c近交系小鼠的CK值高于C57BJ/6J近交系小鼠。Hematological and blood bicohemical Parameters of three stocks of mice were determinated.The results showed:(1)Hematological values:There was significant differences in neutrophil and Lymphocyte cells of BALB/c inbred strain between sexes;There was no significant difference between sexes in C 57 BL/6J inbred strain and KM closed colony.The km mouse had lower white blood\|cell count than that of BALB/c and C 57 BL/6J inbred strain;The BALB/c inbred strain had lower eosinophil and basophilic cells than those of C 57 BL/6J inbred strain and KM mouse.(2)Biochemical values:The C 57 BL/6J inbred strain had higher CHO\,Tbili\,ALT\,AST than those of BALB/c and KM mouse,But the KM mouse had lower Cl than those of BALB/c and C 57 BL/6J inbred strain.The BALB/c inbred strain had higher Ck than those of C 57 BL/6J inbred strain.

关 键 词：小鼠 血液学 血液生化值 

分 类 号：Q461[生物学—生理学] Q95－33