氢化诺卜基甲酸及其酯的合成与结构分析  

Synthesis and Structural Analysis of Hydronopyl Formic Acid and Its Esters

作　　者：刘艳[1] 肖转泉[2] 卢平英[3] 陈金珠[1] 王宗德[1] 范国荣[1] 

机构地区：[1]江西农业大学林学院,江西南昌330045 [2]江西师范大学化学化工学院,江西南昌330027 [3]江西农业大学图书馆,江西南昌330045

出　　处：《林产化学与工业》2013年第4期57-61,共5页Chemistry and Industry of Forest Products

基　　金：林业公益性行业科研专项(201304602)

摘　　要：由氢化诺卜基氯(RCl)与金属镁在乙醚中反应制得氢化诺卜基氯化镁(RMgCl),然后通入二氧化碳并经稀盐酸水解合成了氢化诺卜基甲酸(RCOOH)。在草酸催化下,将氢化诺卜基甲酸分别与甲醇、乙醇、正丙醇、正丁醇、正戊醇和正己醇进行酯化反应,合成了氢化诺卜基甲酸的6种烷基酯,得率在85%以上,酯的GC纯度达98%以上,并对合成的酸与酯进行红外光谱(IR),核磁共振(1H NMR,13C NMR)与质谱(MS)分析,表征了其结构。Hydronopyl magnesium chloride was prepared through the Grignard reaction of hydronopyl chloride and magnesium in solvent of ether. Hydronopylformie acid was obtained from the hydrolyze reaction of diluted hydrochloric acid with the injection of COz. Then six kinds of hydronopylformie acid esters were synthesized from the reaction of hydronopyl formic acid with methanol, ethanol, propanol, butanol, pentanol and hexanol with oxalic acid as catalyst respectively. The yields of the products （ GC con- tents were over 98 % ） were more than 85 %. The structures of the products were characterized and analyzed by IR, 1H NMR, 13C NMR and MS methods.

关 键 词：氢化诺卜基氯 Grignard反应 氢化诺卜基甲酸 酯化反应 结构分析 

分 类 号：TQ351[化学工程] O621[理学—有机化学]