基于三点测交的双标记-QTL基因定位的相关方法  

A Correlation Method for Mapping Quantitative Trait Loci using Flanking Markers in Three-Point Backcross

作　　者：李宏[1] 

机构地区：[1]渝州大学生物系,重庆400033

出　　处：《生物数学学报》2000年第1期93-98,共6页Journal of Biomathematics

基　　金：重庆市科委应用基础研究项目;重庆市教委科研基金资助项目

摘　　要：提出在测交群体中，对区间标记座位赋值后求其与待定位的数量性状表型值间的简单相关系数Ｒ，以此进行连锁测验，并且在一定条件下用Ｒ值求出该数量性状座位（ＱＴＬ）与各标记座位（ＭＬ）间的重组值．In this paper, the author presents new method that gives a value assignment and tries to obtain a simple correlation coefficient R to phenotypic value of quantitative trait in BC population. Then, on the basis, we can go on detecting linkage. Moreover, under certain condition, using R we can estimate the recombination value between quantitative trait loci (QTL) and marker loci (ML).

关 键 词：标记座位(ML) 遗传作图 相关系数 三点测交 

分 类 号：Q348[生物学—遗传学]