糖尿病对老年冠状动脉慢性完全闭塞患者经皮介入治疗后的影响  

Influence of diabetes mellitus on the prognosis of chronic total coronary occlusion in aged patients after percutaneous coronary intervention

作　　者：苏胜[1,2] 邱宁[1,2] 张红[1,2] 谭保平[1,3] 王红[1,3] 

机构地区：[1]广西医科大学第四附属医院 [2]广西壮族自治区柳州市工人医院内分泌科,柳州545005 [3]广西壮族自治区柳州市工人医院心内科,柳州545005

出　　处：《介入放射学杂志》2013年第9期714-717,共4页Journal of Interventional Radiology

摘　　要：目的探讨糖尿病对老年冠状动脉慢性完全闭塞病变患者经皮介入治疗后的影响。方法2008年1月至2011年12月采用经皮介入治疗210例年龄≥65岁的冠状动脉慢性完全闭塞病变患者。根据有无糖尿病病史将患者分为糖尿病组62例和非糖尿病组148例,比较两组术后1年内各种不良心脏事件(死亡、心肌梗死、再次血管重建术)的发生情况和再狭窄、再闭塞发生率。结果非糖尿病组的生存率明显高于糖尿病组,而心肌梗死、靶病变血运重建的发生率则明显低于糖尿病组。结论高水平糖化血红蛋白和糖尿病肾功能损害是冠状动脉慢性闭塞性病变经皮介入治疗后老年患者发生不良心脏事件的独立危险因素。Objective To investigate the influence of diabetes mellitus on the prognosis of chronic total coronary occlusion in aged patients after percutaneous coronary intervention. Methods During the period from Jan. 2008 to Dec. 2011, a total of 210 aged patients （≥ 65 years old） with chronic total coronary occlusion were received percutaneous coronary intervention at the hospital. According to the presence or absence of the history of diabetes mellitus, the patients were divided into diabetes group （n = 62） and non-diabetes group （n = 148）. The occurrence of major adverse cardiac events, including death, myocardial infarction and revascularization surgery, and the incidence of re-stenosis as well as re-occlusion within one year after the treatment were compared between the two groups. Results The survival rate of the non- diabetes group was significantly higher than that of the diabetes group, while the incidence of myocardial infarction and target lesion revascularization of the non-diabetes group was significantly lower than that of the diabetes group. Conclusion This study indicates that high levels of glycosylated hemoglobin and diabetic renal insufficiency are independent risk factors for the occurrence of major adverse cardiac events in aged patients with chronic total coronary occlusion after percutaneous coronary intervention. （J Intervent Radiol, 2013, 22： 714-717）

关 键 词：糖尿病 介入治疗 药物洗脱支架 预测 

分 类 号：R587.2[医药卫生—内分泌]