经典型嗜酸性脓疱性毛囊炎1例  

A Case of Classic Eosinophilic Pustular Folliculitis

作　　者：关杨[1] 杨帆[1] 张芸[1] 莫衍石[1] 

机构地区：[1]深圳市慢性病防治中心皮肤性病科,广东深圳518020

出　　处：《中国皮肤性病学杂志》2013年第9期923-924,共2页The Chinese Journal of Dermatovenereology

摘　　要：患者男,30岁,前额红斑脓疱反复发作1年伴瘙痒,复发1周。前额、眉部、上眼睑大片水肿性红色斑块,其上较密集针帽大小脓疱,部分区域可见鳞屑及结痂。外周血嗜酸性粒细胞百分比7.11%,嗜酸性粒细胞绝对值0.8×109/L;血清TRUST,TPPA及HIV均阴性。脓疱及痂皮真菌镜检均阴性,脓疱细菌培养阴性。组织病理示毛囊、皮脂腺内及周围大量嗜酸性粒细胞及中性粒细胞浸润,PAS染色阴性。诊断:经典型嗜酸性脓疱性毛囊炎。应用雷公藤多甙片60mg/d口服,并外用0.1%他克莫司软膏,治疗2周后皮疹消退,遗留暗红色色素沉着。A 30-year-old man suffered with 1-year history of recurrent erythema and pustules on the forehead and expe- rienced itching for 1 week. There were red edematous plaques on the forehead, eyebrows and upper eyelids 9 with multiple pustules,scales and crusts on it. Laboratory tests showed 7.11% eosinophils （0.8×10^9/L） in peripheral blood and negative for serum TRUST, TPPA and HIV. No bacteria and fungi were found in lesion. Histopathology revealed eosinophil and neutrophil infiltration mainly in and around hair follicles and sebaceous glands. PAS staining was negative. Tile diagnose of classic eosinophilic pustular folliculitis was made. The patient was prescribed with oral glueosidorum tripterygll totorum 60mg/d and topical 0. 1% tacrolimus ointment for 2 weeks. The lesions resolved with slight hyperpigmentation.

关 键 词：毛囊炎 嗜酸性脓疱性 雷公藤多甙片 他克莫司软膏 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]