关于水负荷试验对功能性消化不良评价的调查  

The investigation of water load test for the evaluation of functional dyspepsia

作　　者：李哲[1] 陶琳[1] 肖旸[1] 

机构地区：[1]首都医科大学附属北京中医医院脾胃病科,北京100010

出　　处：《首都医科大学学报》2013年第4期592-595,共4页Journal of Capital Medical University

基　　金：北京市中医药科技基金项目(JJ2010-02)~~

摘　　要：目的分析水负荷试验(water load test,WLT)结果与功能性消化不良(functional dyspepsia,FD)患者性别、年龄、体质量、亚型和心理评分的相关性。方法纳入330例FD患者,记录人口学特征,以WLT测定受试者的阈值饮水量(threshold volume,TV)和饱足饮水量(satiety volume,SV),以汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)和抑郁量表(Hamilton depression scale,HAMD)评价心理状况。结果男性的TV、SV均显著高于女性(P<0.05);WLT结果与HAMA评分呈负相关,与亚型、年龄、体质量、HAMD评分无明显相关性(P>0.05)。结论 WLT评价FD患者胃感觉功能的结果受性别影响,可能和心理因素有关,与亚型、年龄、体质量无关。WLT是一项比较稳定和可靠的评价FD的检查方法。Objective To analyze the correlation between the results of water load test （WLT） and the gender, age, body weight, subtype, psychological rating of functional dyspepsia （FD） patients. Methods In a total of 330 FD patients, the demographic characteristics were recorded, the threshold volume（TV） and satiety volume（SV） were evaluated based on WLT, the psychological status were evaluated based on Hamilton anxiety scale （HAMA） and Hamilton depression scale （HAMD）. Results The TV and SV of males in WLT were significantly higher than those of females（P〈0.05） ; the results of WLT were negatively correlated with HAMA score, and it has no significant correlation with subtype, age, body weight and HAMD score（P〉0.05）. Conclusion Based on WLT, the resuhs of gastric sensory function of FD patients may be affected by gender and anxious psychological factors, which are independent of subtype, age, body weight and depressed psychological factor. WLT is a stable and reliable method for the evaluation of FD.

关 键 词：功能性消化不良 水负荷试验 相关性 

分 类 号：R856.2[医药卫生—航空、航天与航海医学]