儿童过敏性紫癜肾脏损伤发生的相关因素分析  

Analysis of Children Anaphylactoid Purpura with Kidney Injury

作　　者：张霞[1] 丁樱[1] 于文静[1] 任献青[1] 翟文生[1] 

机构地区：[1]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2013年第9期1361-1362,共2页Acta Chinese Medicine

基　　金：国家"十一五"科技支撑项目(编号:2006-BAI04A16)

摘　　要：目的:探讨影响儿童过敏性紫癜(HSP)肾脏损伤发生的相关因素。方法:收集初发及复发的HSP患儿1 882例,依据临床上是否出现尿检异常分为A组(尿检正常组)1 228例及B组(HSPN组)654例,制定调查表,对这些可能因素分别进行单因素及多因素统计分析。结果:年龄、HSP合并腹痛症状及血浆纤维蛋白原升高回归系数分别为1.126、1.223和1.263;相对危险度OR分别为3.134、3.250和3.300。结论:年龄增长、紫癜合并腹痛及血浆纤维蛋白原增高可能是HSP患儿肾脏损伤的重要危险因素。Objective：To investigate the influence of factors associated with children anaphylactoid purpura with kidney injury. Methods： Collect incipient and relapse of HSP patients 1 882 cases. On the basis of clinical abnormal urine test they were divided into group A （normal urine test group） 1 228 cases and group B（ HSPN group） 654 cases. Make the questionnaire and single factor and multi-factor statistical analysis respectively of the possible factors. Results：Age, HSP combined abdominal pain symptoms, and elevated plasma fibrinogen regression coefficient were 1.126,1. 223 and 1.126, respectively. Relative risk OR were 3. 134,3. 250 and 3.134 respectively with 95 % confidence interval. Conclusion：Age, purpura with abdominal pain and increased plasma fibrinogen may be important risk factors of HSP in children with renal damage.

关 键 词：过敏性紫癜 紫癜性肾炎 肾脏损伤 血浆纤维蛋白原 

分 类 号：R395.6[哲学宗教—心理学]