灵活设置胰岛素泵基础率控制围手术期糖尿病患者血糖的临床分析  

Clinical analysis on the basic rate of insulin pump through flexible setting in controlling of blood glucose of patients with diabetics during perioperative period

作　　者：李彦[1] 张先祥[1] 罗涌[1] 王邦琼[1] 王怡[1] 

机构地区：[1]重庆三峡中心医院内分泌科,404000

出　　处：《中国医药》2013年第9期1244-1245,共2页China Medicine

摘　　要：目的探讨灵活设置胰岛素泵基础率控制围手术期糖尿病患者血糖的临床效果。方法将重庆三峡中心医院40例择期手术的2型糖尿病患者按随机数字表法分为试验组（20例）和对照组（20例）。2组患者均使用胰岛素泵，试验组采用固定短时间高剂量基础率代替餐前大剂量输注，对照组采用常规大剂量注射方式。观察2组患者的血糖达标时间、空腹血糖、非空腹血糖、血糖监测次数、低血糖发生率。结果试验组患者血糖达标时间[（3．5±2．2）d]短于对照组[（6．1±2．5）d]，差异有统计学意义（P〈0．05）；空腹血糖[（5．3±1．5）mmol／L]、非空腹血糖[（7．5±2．2）mmol／L]、血糖监测次数[（31±4）次]、低血糖发生率[（5．1±2．4）％]与对照组[（5．6±1．2）mmol／L、（8．1±1．5）mmol／L、（29±6）次、（5．1±2．1）％]比较，差异均无统计学意义（均P〉0．05）。结论灵活设置胰岛素泵，采用固定短时间高剂量基础率代替餐前大剂量输注控制围手术期糖尿病患者血糖是一种安全有效的方法。Objective To explore the clinical effect on the basic rate of insulin pump through flexible set- ring in the controlling of blood glucose of patients with diabetics during perioperative period. Methods Forty type 2 diabetics patients undergoing selective operation in Chongqing Three Gorges Central Hospital were divided into ex- perimental group （20 cases） and control group （20 cease） according to the random number table. Patients of two groups were given insulin pump, experimental group adopted the fixed short time high dose rate instead of the sup- plemental dose infusion, and the control group used conventional high-dose injection. The time of blood glucose con- trolled-compliance, fasting blood-glucose, non-fasting blood glucose, number of blood glucose monitoring and inci- dence of hypoglycemia of two groups were observed. Results There were significant differences on the time of blood glucose controlled-compliance of experimental group [ （ 3.5 ± 2.2 ） d ] when compared with control group （ P 〈 0.05 ）. There were significant differences on fasting blood-glucose, non-fasting blood glucose, number of blood glu- cose monitoring and incidence of hypoglycemia of observation group [ （ 5.3 ± 1.5 ） mmol/L, （ 7.5 ± 2.2 ） mmol,/L, （ 31 ± 4 ） times, （ 5.＇ 1 ± 2.4 ） % ] when compared with control group [ （ 5.6 ± 1.2） mmol,/L, （ 8.1 ± 1.5 ） mmol,/L, （ 29 ± 6） times, （5.1 ± 2.1 ） % ] （ P 〉 O. 05 ）. Conclusion Adopting the fixed short time high dose rate instead of the supplemental dose infusion can be a safe and effective method to control the blood glucose of diabetics in periop- erative period.

关 键 词：糖尿病 胰岛素泵 基础率 血糖 

分 类 号：R587.1[医药卫生—内分泌]