新生儿外周血有核红细胞检测的临床意义  

The significance of NRBC detection in peripheral blood for neonatals in peripheral blood

作　　者：贾中伟[1] 陆琼[1] 陈霁明[2] 汪春新[1] 司力[1] 赵燕[1] 方有兵[1] 

机构地区：[1]安徽医科大学第一附属医院检验科,安徽合肥230022 [2]池州市第二人民医院检验科,安徽池州247100

出　　处：《国际检验医学杂志》2013年第15期1945-1947,共3页International Journal of Laboratory Medicine

基　　金：安徽省教育厅科学研究项目资助(KJ2010A197)

摘　　要：目的探讨新生儿外周血有核红细胞(NRBC)检测的应用价值。方法观察该院住院的160例新生儿患者,利用XE-2100血细胞分析仪测定患儿静脉血NRBC的比例、计数绝对值。结果 71.88%(115/160)的患儿外周血检出NRBC;NRBC检出率与性别无关;外周血检出NRBC的患儿胎龄低于未检出NRBC的患儿(P<0.001);外周血检出NRBC的患儿体质量轻于未检出NRBC的患儿(P<0.001);NRBC比例与计数绝对值,早产儿高于足月儿(P<0.001),低出生体质量患儿高于体质量正常患儿(P<0.01);诊断为新生儿窒息患儿外周血NRBC检出率为100%,NRBC比例与绝对值均高于未诊断出新生儿窒息的患儿(P<0.05)。结论早产儿、低出生体质量儿、新生儿窒息胎儿外周血NRBC计数比例与绝对值均会升高,测定外周血NRBC可用于评价新生儿健康状态.Objective Nucleated red blood cell（NRBC） in peripheral blood of neonate was determined in order to find its clinic value. Methods XE-2100 hematology analyzer was adopted to measure NRBC count percentage and absolute value of 160 cases of neonatal blood samples. Results A total of 115 cases（71.88%） were positive in NRBC detection for peripheral blood. Positive rate of NRBC detection had nothing to do with gender （P= 0. 680）. There was a significant difference between positive and negative NRBC neonates in gestational age（P〈0. 001）. Body weight in positive NRBC neonates was significantly lighter（t= -3. 933, P〈 0. 001）than that in negative NRBC neonates. NRBC percentage and absolute value in premature neonates was significantly higher（P 〈0. 001） than that in full term neonates. The observation did reveal significant difference（P〈0.01） of NRBC percentage and abso- lute value between low birth weight and born with normal weight neonate group. Significant difference（P〈0.05） was also found in NRBC percentage and absolute value between occurrence and no-occurrence of asphyxia. In neonatal with asphyxia NRBC positive rate was 100%. Conclusion In preterm infants,low birth weight infants, neonatal with asphyxia,NRBC count ratio and the abso- lute value of peripheral blood will increase. The measurement of peripheral blood NRBC percentage and absolute value helps evalu- ate neonatal＇s healthg status.

关 键 词：新生儿 早产儿 有核红细胞 窒息 

分 类 号：R446.1[医药卫生—诊断学]