几种炎症标志物在小儿发热疾病中的诊断意义  

The significance of Several inflammatory markers in the diagnosis for children with febrile illness

作　　者：闫慧慧[1] 廖剑[1] 杨湘越[1] 兰小鹏[1] 

机构地区：[1]南京军区福州总医院全军临床检验医学研究所,福建福州350025

出　　处：《国际检验医学杂志》2013年第15期1984-1985,共2页International Journal of Laboratory Medicine

摘　　要：目的研究降钙素原(PCT)、C反应蛋白(CRP)、红细胞沉降率(ESR)和白细胞计数(WBC)在小儿发热疾病中的诊断意义。方法选取2011年6月至2012年2月该院儿科收治的186例发热患儿为研究对象(实验组),采用回顾性分析方法,根据出院时的诊断结果,将其分为感染组,包括细菌、病毒及支原体(n=113)、非感染组(n=63),同时,将健康儿童纳入对照组(n=30)。2组受试儿童的血清PCT、CRP、ESR和WBC检测水平,与对照组健康儿童进行统计学比较。结果感染组患儿PCT、CRP、ESR、WBC较对照组明显升高(P<0.05),但非细菌感染组与对照组之间无明显升高,比较差异无统计学意义(P>0.05)。结论联合检测PCT、CRP、ESR、WBC在小儿发热疾病鉴别诊断中,具有重要意义。Objective To study the diagnostic value of Procalcitonin（PCT） ,C-reactive protein（CRP） ,erythrocyte sedimentation rate（ESR） ,white blood cell（WBC）detection for children with febrile illness. Methods 186 Children received treatment in the hospital from Jul. 201l to Feb. 2012 were recruited in the study（study group）. Retrospective analysis was adopted. According to the di agnostic results when leaving hospital, the study group were divided into 2 smaller groups.- infected group（including bacteria, virus and mycoplasma infection, n= 113） and uninfected group（n=63）. Meanwhile, 30 healthy children were recruited as control group. Results PCT, CRP, ESR,WBC elevated significantly in study group than control group （P〈 0.05）, but there was no statistically significance between infected group and uninfected group（P〉0.05）. Conclusion joint detection of PCT,CRP,ESR,WBC are very important in the diagnosis for children with febrile illness.

关 键 词：发热 降钙素原 C反应蛋白质 血沉 儿童 

分 类 号：R446.6[医药卫生—诊断学]