低蛋白饮食对慢性肾脏病患者肾功能的影响  

Study on influence of low protein intake on renal function in patients with chronic kidney diseases(CKD)

作　　者：朱勍[1] 代文迪[2] 刘文虎[2] 

机构地区：[1]首都医科大学附属北京友谊医院护理教研室,北京100050 [2]首都医科大学附属北京友谊医院肾内科,北京100050

出　　处：《临床和实验医学杂志》2013年第18期1473-1474,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨低蛋白饮食对慢性肾脏病(CKD)患者肾功能的影响。方法回顾性分析慢性肾脏病门诊长期随访的120例慢性肾功能不全的患者根据每日蛋白质摄入的量分成三组:极低蛋白饮食组(VLPD),蛋白摄入量(DPI)≤0.6 g/(kg·d);低蛋白饮食组(LPD),DPI 0.6～0.8 g/(kg·d);正常蛋白饮食组(NPD):DPI≥0.8 g/(kg·d)。对比各组肾功能变化(ΔGFRR)情况。结果不同蛋白饮食组对ΔGFRR影响无显著性差异(P>0.05)。蛋白质饮食与ΔGFRR无显著相关性。结论低蛋白饮食对CKD 2-～5期(非透析)患者无显著的肾脏保护作用。Objective To explore the influence of low protein diet on renal function of patients with chronic kidney diseases （CKD）. Methods A total of 120 patients with chronic kidney diseases were enrolled in this study. According to the level of daily protein intake （ DPI）, all these patients were divided into following groups ： very low protein diet （ VLPD ） group with DPI ≤0. 6 g/（ kg · d） , low - protein diet （LPD） with DPI 0.6 - 0.8 g/（ kg · d）, and normal protein diet group （NPD） with DPI ≥0.8 g/（ kg · d）, and changes in their renal function were compared between all these groups. Results Different DPI had no significant effect on changes of renal function （AGFRR） （ P 〉 0.05 ）. There was no significant correlation between protein diet and A GFRR. Conclusion Low protein diet for patients with CKD at stages 2 - 5 （ non - dialysis） has no significant renal protective effect.

关 键 词：慢性肾脏病 低蛋白饮食 肾功能 

分 类 号：R692.5[医药卫生—泌尿科学]