妊娠晚期孕妇B族溶血性链球菌感染对母儿的影响  

Impact of group B streptococcus infection on late-pregnancy women and their neonates

作　　者：张永[1] 张秦[1] 吴元赭[1] 周迎春 王静 

机构地区：[1]南京军区南京总医院妇产科,南京医学硕士210002 [2]南京明基医院检验科,南京210019

出　　处：《医学研究生学报》2013年第8期833-835,共3页Journal of Medical Postgraduates

摘　　要：目的 B族溶血性链球菌(group B streptococcus,GBS)已被西方国家列为围产期感染的首要病原菌之一。文中探讨孕妇妊娠晚期GBS带菌情况及其是否对母儿产生影响。方法收集产检孕妇共300例临床资料,孕36～38周于阴道下1/3及肛周取材,进行细菌培养。并随访孕妇产褥感染、剖宫产率、产钳助产率、产后出血、胎儿窘迫、新生儿窒息、新生儿黄疸等情况。结果妊娠晚期筛查出GBS阳性者25例,阴性者275例,GBS带菌率为8.3%(25/300)。剔除选择性剖宫产样本后,GBS阳性者剖宫产率大于GBS阴性者(P<0.05),且其胎儿窘迫、新生儿窒息、新生儿病理性黄疸的发生率显著增高,2组产褥感染率、产钳助产率、羊水污染发生率、新生儿败血症及肺炎发生率差异无统计学意义。结论妊娠晚期孕妇感染GBS可对妊娠结局造成不良影响。Objective Group B streptococcus （GBS） has been on the list of primary pathogens of perinatal infections for nearly 40 years in the Western countries. This article is to investigate maternal colonization of GBS in late-pregnancy women and its im- pact on maternal and neonatal outcomes. Methods We cu｜tured vagina｜ and perianal swabs from 300 gravidas at 36 -38 weeks of gestation, screening 25 cases of GBS-positive and 275 cases of GBS-negative. We followed up all the women for the rates of Cesarean section, forceps delivery, postpartum hemorrhage, fetal distress, neonatal asphyxia, neonatal jaundice, puerperal infection, and so on. Results The positive rate of GBS in late pregnancy was 8.3% （25/300）. Excluding the elective cases of Caesarean section, the GBS-positive group showed a significantly higher rate of Cesarean section than the GBS-negative group （P 〈 0.05） as well as obvi- ously higher rates of fetal distress, neonatal asphyxia and neonatal pathological jaundice. There were no statistically significant differ- ences in the rates of puerperal infection, forceps delivery, amniotic pollution, neonatal sepsis and pneumonia. Conclusion GBS in- fection in late-pregnancy women may cause adverse effects on pregnancy outcomes.

关 键 词：B族溶血性链球菌 妊娠晚期 孕妇 

分 类 号：R714[医药卫生—妇产科学]