1％聚桂醇硬化剂治疗下肢毛细血管扩张  

Sclerotherapy for Lower Limb Telangiectasias by 1% Lauromacrogol

作　　者：侯乐伟[1,2] 梅志军[1] 邓国瑜[1] 梁清[1] 景在平[1] 

机构地区：[1]第二军医大学附属长海医院血管外科,上海200433 [2]解放军四五四医院普通外科,南京210002

出　　处：《中国微创外科杂志》2013年第9期796-797,809,共3页Chinese Journal of Minimally Invasive Surgery

摘　　要：目的探讨硬化剂治疗下肢毛细血管扩张的效果。方法2010年9月-2011年7月，运用1％聚桂醇硬化剂注射治疗108例下肢毛细血管扩张，一次治疗总剂量2～10ml，治疗1—2次，治疗后使用长统弹力袜（压力20～30mmHg）至少4周。随访1年，记录毛细血管消退和症状改善情况。结果随访1～12个月，（7．8±2．5）月。97例（90％）扩张毛细血管全部消退，11例（10％）部分消退。57例有症状患者中，28例症状消失，29例症状改善。2例聚桂醇过敏，5例头痛，54例皮下硬结，60例局部皮肤色素沉着（其中10例6个月后仍残留皮肤色素沉着），1例局部皮肤点状坏死。结论聚桂醇硬化注射是治疗下肢毛细血管扩张安全有效的方法，可以改善症状，并极好地解决美容问题。Objective To investigate the effect of sclerotherapy for lower limb telangiectasias by 1% lauromacrogol. Methods 108 patients were treated by 1% lauromacrogol, which was injected by 2 - 10 ml for each treatment and 1 -2 times from September 2010 to July 2011. Thigh-high stockings （20 -30 mm Hg） were required to be worn for at least four weeks after treatment. During the follow-up, degradation of telangiectasias and improvement of symptoms were recorded. Results All cases were followed up for 1 - 12 months （ average, 7.8 ＋ 2.5 months）. Total and partial degradation of telangiectasias were presented in 90% （97/108） and 10% （11/108） of the patients, respectively. Of 57 symptomatic patients, the symptoms of 28 patients disappeared and those of the 29 patients improved. After sclerotherapy, allergy, headache, subcutaneous induration, local cutaneous pigmentation and cutaneous punctiform necrosis were found in 2, 5, 54, 60 and 1 patient, respectively. Pigmentation still retained in 10 of the 60 cases after 6 months. Conclusion Lauromacrogol is a safe and effective sclerosing agent for treating telangiectasias, which can relieve patients＇ symptoms and improve patients＇ cosmetic appearance.

关 键 词：毛细血管扩张 硬化剂治疗 聚桂醇 

分 类 号：R654.4[医药卫生—外科学]