石墨炉原子吸收法测定呋塞米注射液中铝的含量  

Determination of aluminium content in furosemide injection by automatic absorption spectrometry

作　　者：吕斌[1] 李云[1] 郭毅[1] 

机构地区：[1]河南省食品药品检验所化学室,河南郑州450003

出　　处：《河南医学研究》2013年第4期616-618,共3页Henan Medical Research

摘　　要：目的:建立呋塞米注射液中铝含量的测定方法。方法:采用石墨炉原子吸收法测定铝的含量。结果:0.1～1 000 ng.ml-1范围内线性关系良好(r=0.9999),平均回收率(n=6)为99.1%(RSD为2.2%)。结论:石墨炉原子吸收法操作简便快速,结果准确可靠、重复性好,可以用于碱性注射液的质量控制。Objective： To establish a detemination method of aluminium content in the furosemide injection.Method：The automatic absorption spectrometry was used for determination of aluminium with furosemide injection as internal standard.Results： The calibration curve was linear（r=0.9999） in the range of 0.1~1 000 ng·ml-1,the mean recovery was 99.1% and RSD was 2.2%.Conclusion： This method is simple and accurate with a good reproducibility and can be promoted to quality control of alkaline injection.

关 键 词：呋塞米注射液 铝含量 原子吸收测定法 

分 类 号：R917[医药卫生—药物分析学]