结核病专科医院医院感染的调查  

Survey on control of nosocomial infections in TB specialist hospital

作　　者：巩林霞[1] 王元芝[2] 

机构地区：[1]滨州市中心医院神经内科,山东滨州251700 [2]滨州市中心医院手术室,山东滨州251700

出　　处：《中华医院感染学杂志》2013年第15期3697-3699,共3页Chinese Journal of Nosocomiology

摘　　要：目的调查结核病专科医院发生医院感染及其相关危险因素,提出预防医院感染的具体对策。方法采用前瞻性调查结合回顾性分析的方法,对2006年8月-2012年8月入住某结核病专科医院的2000例结核病患者的临床资料进行分析,利用单因素及多元logistic回归分析的方法,对其发生医院感染的危险因素进行分析。结果 2000例结核病患者发生医院感染142例,感染率为7.10%;感染主要发生的部位为下呼吸道73例占51.41%,泌尿道感染15例占10.56%,肠道8例占5.63%;分离出医院感染病原菌134株,其中革兰阴性菌44株占32.84%,革兰阳性菌21株占15.67%,真菌69株占51.49%;采用多元logistic回归分析,年龄大、抗感染类药物的使用、抗结核药物的使用、基础疾病等均为发生医院感染的危险因素(P<0.05)。结论结核病专科医院医院感染的危险因素为患者的年龄大、抗感染类药物的使用、基础疾病等,在实际的预防与控制过程中,应注意对上述危险因素进行控制,从而减少医院感染的发生率。OBJECTIVE To explore related risk factors of the nosocomial infections in tuberculosis specialist hospital by surveying the incidence of nosocomial infections so as to put forward the specific strategies for the control of nosocomial infections in the TB specialist hospital. METHODS By means of prospective survey combined with the retrospective survey, the clinical data of 2000 cases of patients with tuberculosis were analyzed from Aug 2006 to Aug 2012, then the univariate analysis and the multivariate logistic regression analysis were carried out to analyze the risk factors of nosocomial infections. RESULTS Of the 2000 cases of TB patients, the nosocomial infections occurred in 142 cases with the infection rate of 7.10%, among which there were 73 （51.41%） cases with lower respiratory tract infections, 15 （10.56 %） cases with urinary tract infections, and 8 （5.63 %） cases with intestinal tract infections. There were totally 134 strains of pathogens isolated, including 44 （32.84%） strains of gram- negative bacteria, 21 （15.67%） strains of gram-positive bacteria, and 69 （51.49%） strains of fungi. The multi- variate logistic regression analysis showed that the advanced age, use of antibiotics for anti-infection therapy, use of anti-TB drugs, and underlying disease were the risk factors of nosocomial infections （P〈0.05）. CONCLUSION The risk factors of nosocomial infections in the TB specialist hospital include the advanced age, the use of anti-in- fection drugs, and the underlying diseases, and during the prevention and control process, it is necessary to pay attention to the risk factors listed above so as to reduce the incidence of nosocomial infections.

关 键 词：结核病专科医院 医院感染 调查 感染部位 

分 类 号：R181.32[医药卫生—流行病学]