壳聚糖创伤敷料膜的研究与应用进展  

Researches and Applications Progress of Chitosan-Based Wound Dressing Film

作　　者：周群飞[1] 敖宁建[2] 

机构地区：[1]暨南大学生物工程学系 [2]暨南大学生物医学工程系,广州510632

出　　处：《高分子通报》2013年第8期68-75,共8页Polymer Bulletin

基　　金：国家自然科学基金资助项目(No.20976068/B060805)

摘　　要：壳聚糖作为广泛存在于天然界中的天然高分子聚合物甲壳素的脱乙酰化产物,不仅具有良好的生物相容性、生物降解性、低毒性、成膜性等性质,还具有止痛止血、抗菌消炎、缓释药物等生物活性。壳聚糖及其衍生物已被广泛应用于医药领域,并逐渐成为制备皮肤创伤敷料膜的首选材料。本文结合壳聚糖的结构特征,以及用于治疗皮肤创伤的相关性能,综述了利用壳聚糖及其衍生物制备性能优异的皮肤创伤敷料膜的研究进展,并在此基础上对其应用前景做出了展望。As the deacetylated product of chitin, a polymer abundant in nature, chitosan has a range of outstanding properties such as biocompatibility, biodegradability, nontoxicity, film-forming ability, and bioactivities e.g. acesodyne, hemostatic, antibacterial, antiphlogistic and drug delivery properties. As a result, chitosan has a great potential for a wide range of applications in medicine, especially in preparing wound dressing film. This paper highlights the properties of chitosan in treating skin wounds, and the research progress of the wound dressing with excellent property prepared via ehitosan and its derivates is reviewed.

关 键 词：壳聚糖 衍生物 敷料膜 应用 

分 类 号：R318.08[医药卫生—生物医学工程]