影响实验动物慢性心理应激反应的因素  

Influencing Factors of Experiment Animals’s Response in Chronic Psychological Stress

作　　者：薛亮[1] 张逸[1] 朱熊兆[1] 

机构地区：[1]中南大学湘雅二医院医学心理学研究所,长沙410011

出　　处：《中国临床心理学杂志》2013年第4期549-552,571,共5页Chinese Journal of Clinical Psychology

基　　金：国家自然科学基金(81071097)

摘　　要：动物慢性心理应激是研究焦虑症、抑郁症以及情绪障碍等人类的精神疾病比较常用的方法。在动物实验中,慢性应激对动物的影响是多方面、持久的并且比较复杂,包括神经内分泌、免疫系统以及行为学的变化等,这些变化的原因可以分为应激源因素如应激源类型、应激强度和应激时间等以及非应激源因素如实验动物年龄、性别、种属等。本文旨在探讨这两种因素在慢性心理应激中的影响,以便对将来的研究提供参考和借鉴。The chronic psychological stress of the animals is the commonly used method to study human mental disor- ders, such as anxiety,depression and mood disorders. In animal experiments, the effects of chronic stress are extensive, lasting and complicated, including neuroendocrine system, immune system and behavior changes, the reasons of these changes can be divided into two aspects： Stress source factors such as stress source type, stress intensity and stress time; the NOT-Stress source factors, Such as age, gender, species of laboratory animals. This paper discusses the influence of the two factors in the chronic psychological stress, so as to provide a reference for the future researches.

关 键 词：慢性心理应激 神经内分泌 行为 

分 类 号：R395.1[哲学宗教—心理学]