肝移植受者焦虑抑郁状态及其影响因素研究  

Anxiety and depression of liver transplant recipients and the related impact factors

作　　者：廖苑[1] 郑宗珩[2] 韩明[1] 潘雄英[1] 伍梅娟[1] 成守珍[1] 

机构地区：[1]中山大学附属第一医院器官移植科,广州510080 [2]中山大学附属第三医院胃肠外科

出　　处：《中华器官移植杂志》2013年第9期537-541,共5页Chinese Journal of Organ Transplantation

基　　金：广东省医学科学基金（132011082）;广东省自然科学基金（（17001681）

摘　　要：目的评价肝移植受者的焦虑、抑郁状态及其影响因素。方法在移植前及移植后1、6、12、24和36个月，采用一般情况调查表、焦虑自评量表、抑郁自评量表和社会支持评定量表对42例肝移植受者进行问卷调查。结果移植前及移植后1、6、12、24和36个月受者焦虑评分分别为37．2±5．3、32．2±6．2、32．1±6．6、31．9±5．1、30．1±4．6和28．5±4．1，抑郁评分分别为46．7±7．1、37．9±10．7、36．7±7．9、37．1±6．4、34．3±5．8和32．1±5．6。肝移植受者术前至术后各时间段的焦虑评分的差异有统计学意义（P〈0．001），抑郁评分的差异有统计学意义（P〈0．001）；术后各时间点至术后36个月间受者焦虑评分的差异有统计学意义（P〈0．001），抑郁评分的差异有统计学意义（P〈0.001）。肝移植术后受者焦虑的影响因素为主观支持、支持利用度。抑郁的影响因素为术前抑郁评分、客观支持、主观支持、支持利用度。结论肝移植受者术后焦虑及抑郁状态较术前减轻，术后3年时受者焦虑及抑郁状态较术后0～2年时轻。Objective To evaluate the anxiety and depression status of the liver transplant recipients and to investigate the related impact factors. Method Forty-two liver transplant recipients were under survey by General Information Questionnaire （GIQ）, Social Support Rating Scale （SSRS）, Self-rating Anxiety Scale （SAS） and Self-Rating Depression Scale （SDS） before and 1, 6, 12, 24 and 36 months after operation. Result The mean anxiety scores before and 1, 6, 12, 24 and 36 months after operation were 37. 2 ± 5.3, 32. 2 ± 6. 2, 32. 1 ± 6. 6, 31.9 ± 5. 1, 30. 1 ± 4. 6 and 28. 5 ± 4. 1, respectively. The mean depression scores at those 6 time points were 46. 7 ± 7. 1, 37. 9 ± 10. 7, 36. 7 ± 7. 9, 37. 1 ± 6. 4, 34. 3 ± 5. 8 and 32. 1 ± 5.6, respectively. Both the anxiety and depression scores showed statistically significant difference （P〈0. 001） before and after operation （all time points）. Also there was statistically significant difference （P〈0. 001） between post-operative month 36 and other post-operative time points. The impact factors for anxiety of liver transplant recipients were subjective supports and the utilization level of the supports. The impact factors of depression of liver transplant recipients were pre-operative depression score, objective support, subjective supports and the utilization level of the supports. Conclusion Liver transplant recipients suffer less anxiety and depression after operation. The anxiety status can be further improved from 24 to 36 months postoperation.

关 键 词：肝移植 受者 焦虑 抑郁 危险因素 社会支持 

分 类 号：R657.3[医药卫生—外科学]