基于胸阻抗的人体肺功能参数测量方法  

A new method for measuring pulmonary function parameters

作　　者：杨建明[1] 钟胜河[1] 梁妃学[1] 郭劲松[1] 李伟龙 李金明[1] 

机构地区：[1]南方医科大学基础医学院生物信息学系,广东广州510515 [2]杨森电子科技有限公司,广东广州510515

出　　处：《南方医科大学学报》2013年第9期1352-1356,共5页Journal of Southern Medical University

基　　金：广东省科技计划项目(2010A030500007;2011B010200009);广州市科技计划项目(11A32120831)

摘　　要：目的研制一种基于人体胸阻抗变化的测量,获取人体肺功能参数的新方法。方法基于生物阻抗法研究用力呼吸过程中胸阻抗的变化与肺功能参数值的关系,研制了胸阻抗测量仪实验样机,分别采用所研制的实验样机和基于传统流量计进行肺功能测量的MIR公司的spirolabⅢ肺功能仪,对10例健康人进行对比实验,所测肺功能参数包括:用力肺活量、一秒率和峰值流量。结果所测数据均落于其均值的正负两倍标准差范围之内因为两种方法具有较好的一致性。结论基于生物阻抗法研制的实验样机所测肺功能参数与市售肺功能仪(基于流量计测量方法)的测量结果有较好的一致性。Objective To propose a new method for acquiring pulmonary function parameters based on measurement of volume changes of thoracic impedance. Methods We studied the relationship between the volume changes of thoracic impedance and pulmonary function parameters during forced breathing based on bioimpedance measurement, and developed an instrument for measuring thoracic impedance. Using this instrument and a MRI spirolab III lung function test instrument, both based on flowmeter measurement, we measured such pulmonary function parameters including forced vital capacity （FVC）, forced expiratory volume in one second/FVC （FEV1/FVC）, and peak expiratory flow in 10 healthy volunteers and compared the measurement results. Results The differences in the parameters measured using the two instruments were all within two folds of the positive and negative standard deviations of the average values, demonstrating good consistency in the measurement between the two methods. Conclusions The measurement results of the bioimpedance-based instrument we developed show good consistency with those by the commercially available pulmonary function test instrument.

关 键 词：胸阻抗 阻抗变化 用力肺活量 一秒率 峰值流量 

分 类 号：R563.9[医药卫生—呼吸系统]