2010—2012年新疆HIV感染产妇及其所生婴儿应用抗艾滋病病毒药物状况分析  

Analysis on anti HIV drug application among HIV positive mothers and their children in Xinjiang,2010-2012

作　　者：沙吾力.艾力卡 崔丹[1] 艾比拜.买买提明 关灵灵[1] 王磊[1] 

机构地区：[1]新疆维吾尔自治区疾病预防控制中心,新疆乌鲁木齐830002

出　　处：《中国健康教育》2013年第8期687-689,共3页Chinese Journal of Health Education

摘　　要：目的了解新疆HIV感染产妇及其所生婴儿抗艾滋病病毒药物应用状况及变化趋势。方法对预防艾滋病母婴传播管理信息网络直报系统中报告的2010—2012年间分娩的1303例HIV感染产妇及其所生婴儿抗病毒药物应用情况进行描述性分析。结果 1303例HIV感染产妇中,2010—2012年分别有72.58%、77.40%和79.55%的产妇应用了抗病毒药物,并呈逐年上升趋势(χ2=6.30,P<0.05),HIV感染产妇孕28周及以前开始应用三联方案比例也呈逐年上升趋势(χ2=13.81,P<0.01);HIV感染产妇所生婴儿抗逆转录病毒药物应用比例分别为77.63%、84.91%和84.09%,2011年比2010年上升幅度比较明显,2012年比2011年略有下降(χ2=8.82,P<0.01)。结论 HIV感染产妇及所生婴儿抗病毒药物应用比例逐年上升,但仍有较大的上升空间,需要进一步提高HIV感染产妇及其所生婴儿抗病毒药物应用比例,从而减少母婴传播的风险。Objective To understand the anti-HIV drug application status and its trends among HIV-infected mothers and their children in Xinjiang. Methods Reports from Management system of HIV mother-to-child transmission pre- vention network were analyzed from 2010 to 2012, 1303 cases of antiviral drugs application among HIV-infected mothers and their children were carried out descriptive analysis. Results During 2010 -2012, among 1303 HIV positive lying-in women, there was 72. 58%, 77. 40% and 79. 55% of them used antiviral drugs with an increased trend by years （Х^2 = 6. 30, P 〈 0. 05 ）. There was an upward trend in the ratio of joint solution use beginning among HIV positive pregnant women before the 28th week of gestation （Х^2 = 13.81, P 〈 0. 01 ）. The antiretroviral drugs application proportions among children of HIV-infected pregnant women were 77. 63% , 84. 91% , 84. 09%, and the obvious increasing in 2011 than in 2010, declined slightly in 2012 than in 2011 （X2 = 8.82, P 〈 0. 01 ）. Conclusion Antiviral drugs application proportions among HIV positive pregnant women and their infant increased year by years, but there were still a larger rising space. It is need to further improve antiviral drugs application proportion among them to reduce the risk of mother-to-child transmission.

关 键 词：HIV 产妇 婴儿 艾滋病病毒药物 

分 类 号：R193[医药卫生—卫生事业管理] R512.91[医药卫生—公共卫生与预防医学]