2008~2012年杭州地区招聘人员梅毒血清学检测结果分析  

Analysis of the Results of Syphilis Serology for Recruiters from 2008 to 2012 in Hangzhou

作　　者：金美彤[1] 戴玉柱[1] 王国政[1] 周华君[1] 张群[1] 车飞虎[1] 杨琼[1] 王磊[1] 徐莉[1] 孙长贵[1] 成军[1] 

机构地区：[1]解放军第117医院检验科,杭州310013

出　　处：《现代检验医学杂志》2013年第4期129-132,共4页Journal of Modern Laboratory Medicine

摘　　要：目的 了解2008～2012年杭州地区招聘人员梅毒螺旋体感染情况.方法 采用梅毒快速血浆反应素试验（RPR）和明胶凝集法梅毒螺旋体抗体试验（TPPA）对2008～2012年20 876例招聘人员进行梅毒血清学筛查,阳性结果采用免疫印迹试验（WB）进行确认,并按年度、年龄、拟聘职业及性别分组进行统计分析.结果 20 876例招聘人员的梅毒阳性检出率为0.44%（91/20 876）,呈缓慢的逐年增长（χ2=8.12,P〈0.01）,男性梅毒总阳性例数、TPPA单项阳性数及RPR/TPPA双阳性数均高于女性（χ2=8.34～19.23,P均〈0.01）;三个年龄组之间（〈30岁,31～40岁,〉41岁）的梅毒检出率差异有统计学意义（χ2=39.03～135.53,P均〈0.01）,且随年龄增加而上升（χ2=131.18,P〈0.01）;在五个职业类别中,服务业员工的梅毒阳性检出率最高（1.85%,22/1 186）,国家公务员、企事业员工最低,分别为0.04%,0.05%.结论 招聘人员的梅毒感染率处于较低水平,但呈逐年缓慢上升趋势,应将梅毒血清学筛查试验作为招聘人员体检的必检项目,对有争议或可疑的结果应采用免疫印迹试验（WB）进行确认,从而有效控制梅毒流行.Objective To investigate the situation of syphilis infection in recruitment examinations from 2008 to 2012 in Han- gzhou. Methods The serum syphilis antibody of 20 876 recruiters from 2008 to 2012 was detected by the rapid plasma rea- gin（RPR） and gelatin agglutination test（TPPA）. The positive results were confirmed by immunoblotting test（WB） and were statistically analyzed according to the annual,age,occupation,gendergroup. Results The positive rate of syphilis infection was 0. 44 % （91/20 876） in 20 876 recruiters,and a slowly increasing（xz = 8.12,P〈0. 01）. The total number of positive ea- ses,TPPA single positive numbers and RPR/TPPA double positive numbers of syphilis infection in male was higher than that in female（x2 = 8.34 ~ 19.23, P〈0. 01）. the detection rate of syphilis （including previous infection） was significant difference（x2= 239.03~ 135.53,P〈0. 01） among the three age groups（〈30y, 31~40y, 2〉41y）, and increased with age（x2 = 131.18 ,P〈0.01）. In the five occupation categories, the positive rate of syphilis infection was highest（1.85 %, 22/1 186） in service industry, and the civil service,enterprise or business was the lowest with 0.04 %, 0. 05 %, respectively. Conclusion The rate of syphilis infection showed a lower level but slowly rising trend year by year in recruitment examinations. The syphilis serological screening test should be necessary inspection item in recruitment examinations. The immunoblotting test （WB） should use on controversial or questionable results for confirmation,so as to effectively control the prevalence of syph- ilis.

关 键 词：梅毒 招聘体检 血清学筛查 梅毒快速血浆反应素试验 梅毒明胶颗粒凝集试验 免疫印迹试验 

分 类 号：R759.1[医药卫生—皮肤病学与性病学] R446.62[医药卫生—临床医学]