临床药师协同行政干预促进抗菌药物的合理应用  

Clinical Pharmacists Collaborative Administrative Intervention to Promote the Reasonable Application of Antibiotics

作　　者：谭丽蓉[1] 王芳[1] 梁少芳[1] 余新立[2] 苏炜[1] 

机构地区：[1]江门市中心医院药学部,广东江门529030 [2]江门市中心医院医务科,广东江门529030

出　　处：《今日药学》2013年第8期522-524,共3页Pharmacy Today

基　　金：江门市科技计划项目(编号:12-49)

摘　　要：目的探讨临床药师协同行政干预对促进抗菌药物合理应用的作用。方法回顾性分析卫生部抗菌药物临床应用专项整治活动前后本院抗菌药物临床合理应用各项指标。结果整治前后门诊、住院患者抗菌药物应用率分别由18.48%和59.31%降至16.52%和42.77%;抗菌药物使用强度由64.73 DDD降至43.65 DDD;标本送检率由51.57%升至62.66%;Ⅰ类切口手术和介入治疗患者预防使用抗菌药物比例由98.49%降至42.20%,预防用药时间不超过24 h的比例由9.06%升至64.95%;外科手术预防用药时机正确率从4.51%上升到73.14%。结论临床药师协同行政干预可明显提高抗菌药物的临床合理应用,但要完全达到卫生部的要求还需进一步努力。Objective To explore the effects of clinical pharmacists collaborative administrative intervention to promote the reasonable application of antibiotics.Methods Retrospective analysis method was adopted to analyze the indications of clinical reasonable application of antibiotics before and after rectification.Results The ratio of antibacterial prescription in outpatients and the application ratio of antibacterial in inpatients decreased from 18.48% and 59.31% before rectification to 16.52% and 42.77% after rectification.The average value of Antibiotics Use Density（AUD） dropped from 64.73 DDD to 43.65 DDD.The specimen inspection rate increased from 51.57% to 62.66%.The prophylactic application ratio of antibacterial in type Ⅰincision operation and interventional therapy declined from 98.49% to 42.20%.The ratio of prophylactic usage time is less than 24 hours increased from 9.06% to 64.95%.The accuracy of the time of first dose in surgical preventive medicine increased from 4.51% to 73.14%.Conclusion Clinical pharmacists collaborative administrative intervention can obviously improve the reasonable application of antibiotics.However,further development of the rectification should be made to come up to the requirement of Ministry of Health.

关 键 词：抗菌药物 临床药师 行政干预 合理用药 

分 类 号：R97[医药卫生—药品]