超高N-末端脑利钠肽值(NT-pro BNP)和心率震荡(HRT)对心衰患者临床价值的分析  

High N-terminal Brain Natriuretic Peptide Values(NT-pro BNP)and Heart Rate Turbulence(HRT)Analysis of Clinical Value in Patients with Heart Failure

作　　者：赵玉红[1] 黄真辉[1] 吴敬伟[1] 陈爱军[1] 金雅琼[1] 卢飞[1] 秦桂华[1] 

机构地区：[1]上海市松江区泗泾医院内科,201601

出　　处：《医学理论与实践》2013年第17期2243-2244,2266,共3页The Journal of Medical Theory and Practice

基　　金：上海市松江区科委攻关项目(12SJGGYY54)资助课题

摘　　要：目的:测定老年慢性心衰患者的血浆N-末端脑钠素前体(NT-pro BNP)和心率震荡(HRT)水平,探讨血浆NTPro BNP和HRT值对心衰的临床价值的评估。方法:选择本院住院心力衰竭(CHF)的住院患者80例组成,其中男、女比例不限;对照组80例,为心功能正常者。两组年龄、性别差异无显著意义(P>0.05),具有可比性。心衰患者测定NT-pro BNP>5 000pg/ml和TS≤3.0的患者。分为好转组和死亡组。随访1年。两组比较分析。结果:老年CHF患者与老年健康者NT-pro BNP、窦性HRT存在明显差别(P<0.05);老年CHF组NT-pro BNP(4 967.04±366.16)pg/ml明显高于对照组(416.21±146.54)pg/ml(P<0.001);老年CHF组TO(0.76±3.42)明显高于对照组(-1.61±2.05)(P<0.05);老年CHF组TS(2.53±1.21)明显低于对照组(9.56±4.03)(P<0.05)。老年CHF组LVEF(38.37±12.15)%明显低于对照组的(66.52±13.05)%(P<0.05)。结论:慢性心衰患者的NT-pro BNP>5000pg/ml和TS≤3.0死亡率高。Objective：Determination of plasma N-terminal pro brain natriuretic peptide in elderly patients with chronic heart failure （NT-pro BNP） body and heart rate turbulence （HRT） level, evaluation of plasma NT-pro BNP and HRT clinical value of the heart failure. Methods：The hospitalized heart failure （CHF） of 80 cases of patients, male, female ra- tio is not restricted; control group： 80 patients, for patients with normal cardiac function. No significant gender differ- ences in two age groups, （P〉0. 05）, with comparable. Determination of NT-pro BIN-P, 5 000pg/ml in patients with heart failure and TS ≤ 3 patients. Divided into improved group and death group. 1 year of follow-up. Comparative analysis of two groups. Results： In elderly CHF patients and healthy elderly subjects NT-pro BNP, sinus HRT significant differences （P〈0. 05） ; elderly group CHF NT-pro BNP （4 967. 04± 366.16） pg/ml was significantly higher than the control group （416. 21±146. 54）pg/ml（P〈 0. 001）;aged CHF group TO（0. 76±3. 42） was significantly higher than that of control group （- 1.61 ± 2. 05） （P〈0. 05） ;aged CHF group TS （2. 53 ±1.21） was significantly lower than that of the control group （9. 56±4. 03） （P〈0. 05）. The aged CHF group LVEF （38. 37±12. 15）% was significantly lower than that of the control group （66. 52± 13.05）% （P〈0. 05）. Conclusion： In patients with chronic heart failure NT-pro BNP, 5 000pg/ml and TS≤ 3 high mortality.

关 键 词：超高NT-pro BNP HRT 心衰患者 

分 类 号：R541.6[医药卫生—心血管疾病]