新生儿梅毒29例临床研究  

Clinical Study on 29 Cases of Syphilis in Neonates

作　　者：张健 陆峰 何敏 

机构地区：[1]江苏泗洪儿童医院,223900

出　　处：《医学理论与实践》2013年第18期2402-2403,2417,共3页The Journal of Medical Theory and Practice

摘　　要：目的:探讨新生儿梅毒的诊断及防治要点。方法:回顾性分析29例新生儿梅毒患儿的临床资料,分析患儿的临床特点,总结诊治经验。结果:新生儿梅毒患儿临床表现各异,不典型,无特异性表现,确诊要靠辅助检查;绝大部分患儿父母感染梅毒后,部分由于无症状或症状不明显,未及时正规治疗,且存在隐瞒病史,导致诊断困难;治疗上首选青霉素,对青霉素治疗无效的选用阿奇霉素。结论:新生儿出生后特别是一些早产儿,症状上有多器官功能损害而又不能以现有疾病解释的患儿,应及时做血清梅毒螺旋体RPR、TPHA检查及四肢长骨X线检查。治疗上首选青霉素,不敏感者给予阿奇霉素。早诊断,早治疗,愈后较好,但部分患儿可能会致死亡或留下后遗症。同时要积极开展性病防治和宣传工作,减少先天性梅毒的发病率。Objective：To explore the diagnosis of syphilis in neonates and prevention and treatment of points. Methods： A retrospective analysis of 29 cases of syphilis in newborn children with clinical information, analysis of clinical charac- teristics in children with summarizing the experiences of diagnosis and treatment. Results： In children with different clin- ical manifestations of syphilis in neonates,atypical, no specific performance diagnosis must rely on auxiliary examina- tion;after the vast majority of parents of children with syphilis,due in part to no symptoms or symptoms is not obvi- ous, not regular treatment in time, and hide the history, make diagnosis difficult; preferred in the treatment of penicillin, penicillin treatment using azithromycin. Conclusion： Especially in premature infants after birth, on symptoms and multi- ple organ dysfunction in children with existing diseases cannot be explained, should have serum Rotary body RPR and TPHA syphilis examination in a timely manner and long bone X-ray. Preferred in the treatment of penicillin, agie insen- sitive given adriamycin. Early diagnosis, treatment, prognosis is better, but some children may result in death or leave sequelae. While actively STD prevention and advocacy work, reducing the incidence of congenital syphilis.

关 键 词：新生儿 梅毒 研究RPR TPHA 

分 类 号：R722.13[医药卫生—儿科]