头孢曲松钠肛门滴入治疗小儿细菌性痢疾的疗效观察  

Observation of the effect of ceftriaxone sodium anal trickle in the treatment of pediatric bacillary dysentery

作　　者：张连涛[1] 

机构地区：[1]商丘市第一人民医院分院传染科,河南省商丘476100

出　　处：《中国基层医药》2013年第22期3393-3394,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨头孢曲松钠肛门滴入治疗小儿细菌性痢疾（菌痢）的临床疗效。方法62例菌痢患儿按数字表法随机分成观察组与对照组，两组例数均为31例。观察组接受头孢曲松钠肛门滴人，对照组口服环丙沙星。对两组各项症状消失时间及临床疗效进行对比。结果观察组腹痛消失时间、腹泻消失时间、退热时间及粪便涂片转阴时间分别为（3．97±1．05）d、（3．52±1．35）d、（1．62±0．57）d、（3．12±0．74）d，均明显短于对照组的（5．37±0．86）d、（4．85±1．22）d、（3．24±1．35）d、（4．43±1．04）d（t=5．743、4．070、6．155、5．714，均P〈0．05）；观察组总有效率为96．8％，对照组总有效率为93．5％，两组总有效率差异无统计学意义（Z=0．917，P〉0．05）。结论头孢曲松钠肛门滴人治疗小儿菌痢起效快，疗效显著且副作用小，值得推广。Objective To explore the clinical effect of ceflriaxone sodium anus drip in the treatment of chil- dren with bacillary dysentery （shigellosis）. Methods 62 children with bacillary dysentery were randomly divided in- to observation group and control group, 31 cases in each group. The observation group received ceftriaxone sodium anus drip, while the control group received oral ciprofloxacin. The symptoms disappeared time and clinical effect of two groups were compared. Results In the observation group, the disappearance time of abdominal pain, diarrhea, fever and the fecal smear negative time were （ 3.97 ±1.05 ） d, （ 3.52 ±1.35 ） d, （ 1.62 ±0.57 ） d, （ 3.12 ±0.74 ） d, which were significantly shorter than those in the control group （5.37 ±0.86） d, （4.85 ±1.22 ） d, （ 3.24 ±1.35 ） d, （4.43 ±1.04） d（ t = 5. 743,4.070,6. 155,5. 714, all P 〈 0.05 ）. The total effective rate of the observation group was 96.8% , that of the control group was 93.5%, the difference between the two groups was not significant （Z = 0. 917,P 〉 0. 05）. Conclusion Ceftriaxone sodium anal trickle has significant effect in the treatment of pediatric bacillary dys- entery and it takes effect very quickly, so it is worthy of promoting.

关 键 词：头孢曲松钠 投药 直肠 痢疾 杆菌性 

分 类 号：R725.1[医药卫生—儿科]