An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range  

作　　者：CHEN DongYang SHI JianBing WU YanMei TONG Bin ZHI JunGe DONG YuPing 

机构地区：[1]School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China [2]School of Chemistry, Beijing Institute of Technology, Beijing 100081, China

出　　处：《中国科学：化学》2013年第9期1213-1213,共1页SCIENTIA SINICA Chimica

摘　　要：Polyelectrolyte PTPEPyH,containing tetraphenylethene(TPE)and pyridinium,was synthesized.Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin.The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings.The polyelectrolyte PTPEPyH,compared with ChS and HA,also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.Polyelectrolyte PTPEPyH, containing tetraphenylethene （TPE） and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

关 键 词：聚电解质 肝素 检测范围 荧光探针 传感 生物大分子 硫酸软骨素 光学特性 

分 类 号：O657.3[理学—分析化学]