miRNAs对肠道健康的调控作用及机理  

miRNAs:Regulation on Intestinal Health and Mechanisms

作　　者：陶新[1] 徐子伟[1] 

机构地区：[1]浙江省农业科学院畜牧兽医研究所,杭州310021

出　　处：《动物营养学报》2013年第9期1911-1915,共5页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金(31101725);国家现代农业产业技术体系(CARS-36);浙江省重点科技创新团队项目(2010R50027)

摘　　要：本文在介绍肠道组织miRNAs表达的基础上,主要就miRNAs的差异表达对肠道上皮细胞增殖、分化、凋亡的影响以及miRNAs在肠道黏膜免疫、抵御外界病原感染、抗应激、调节肠道营养代谢和维持肠道稳态等方面所起的作用及其机理进行了综述。Based on introduction of the expression of miRNAs in intestinal tissue, this article mainly reviewed the effects of differential miRNAs expression on the proliferation, differentiation and apoptosis of intestinal epithelial cell, and the regulation of miRNAs on intestinal mucosal immunity, disease resistance, anti-stress responses, metabolic modulation through nutrition and preserving intestinal homeostasis, etc, and their mechanisms.

关 键 词：MIRNAS 肠道 肠道上皮细胞 肠道黏膜免疫 肠道稳态 

分 类 号：S852.2[农业科学—基础兽医学]