顶空进样-气相色谱-质谱法检测清洁类化妆品中环氧乙烷和环氧丙烷残留量  

Determination of Ethylene Oxide and Methyloxirane in Clean Cosmetics by Headspace Sampling-Gas Chromatography-Mass Spectrometry

作　　者：张敬轩[1] 李挥[1] 蔡立鹏[1] 范斌[1] 张岩[1,2] 

机构地区：[1]国家环保产品质量监督检验中心,河北省食品安全实验室,石家庄050091 [2]河北医科大学,石家庄050017

出　　处：《分析化学》2013年第8期1293-1294,共2页Chinese Journal of Analytical Chemistry

基　　金：河北省科技支撑项目基金(Nos.12967150D;12396907D)资助项目

摘　　要：1引言环氧乙烷和环氧丙烷一般存在于以聚乙二醇、聚丙二醇类结构物质为原料的化妆品中,特别是洗面奶、洗发水等清洁类产品,由于其具有致突性和致癌性,欧盟法规和我国《化妆品卫生规范》（2007版）[1]均将其列入禁用物质,国内尚无标准检测方法。A method based on headspace sampling-gas chromatography-mass spectrometry（HS-GCMS） was developed for the qualitative and quantitative detection of ethylene oxide and methyloxirane in clean cosmetics.About 1.0 g of sodium chloride and 5.0 mL of deionized water was added to the sample.After vortex mixed,the mixture above was placed in a headspace sampler,and then qualitative and quantitative analysis was carried out by HS-GCMS with SIM model.The calibration curve was linear in the range of 1.0-100.0 μg（ethylene oxide） and 0.5-50.0 μg（methyloxirane） with R0.995.The detection limits were 0.02 μg（ethylene oxide） and 0.01 μg（methyloxirane）,and the quantitative limit were 0.07 μg（ethylene oxide） and 0.03 μg（methyloxirane）.By determination to 15 batches cleanser,15 batches shampoo and 20 batches bath foam bought in the supermarket,we found that this method was suitable for the determination of ethylene oxide and propylene oxidein.

关 键 词：清洁类化妆品 标准检测方法 气相色谱-质谱法 环氧丙烷 环氧乙烷 顶空进样 残留量 《化妆品卫生规范》 

分 类 号：TQ658[化学工程—精细化工] O657.63[理学—分析化学]