分蘖葱头中新黄酮苷的结构鉴定  

A NEW FLAVONOID GLYCOSIDE FROM ALLIUM CEPA L. VAR AGROGATUM DON

作　　者：杨晓虹[1] 刘银燕 刘丽娟[1] 周小平[1] 铃木敏夫[2] 

机构地区：[1]白求恩医科大学药学院药物化学教研室,吉林长春130021 [2]日本秋田大学医学部附属病院药剂部

出　　处：《药学学报》2000年第10期752-755,共4页Acta Pharmaceutica Sinica

基　　金：国家留学基金管理委员会资助!(留金法 [1999] 5 0 0 3号 )

摘　　要：目的　研究百合科植物分蘖葱头 (AlliumcepaL .varagrogatumDon)鳞茎的黄酮类化学成分。 方法　利用SephadexLH 2 0柱色谱进行分离纯化。从分蘖葱头中分离得到 4个化合物 ,用IR ,UV ,MS ,1HNMR ,13CNMR ,1H 1HCOSY ,1H 13CCOSY和HMBC等光谱鉴定化合物。结果　经光谱鉴定化合物结构为 :槲皮素 3′ 甲氧基 4′ O β D 葡吡喃糖苷 (I)、山奈酚 (II)、槲皮素 4′ O β D 葡吡喃糖苷 (III)和槲皮素 3 ,4′ 二 O β D 葡吡喃糖苷 (IV)。结论　化合物I为新的黄酮苷类化合物 ,命名为分蘖葱头苷甲 (AlliumosideA) ;II ,III和IV为首次从该植物中分得。AIM To investigate the chemical constituents from the bulb stems of the Chinese medicinal plant Allium cepa L. var. agrogatum Don. METHODS The crude extracts of the bulb stem were purified by Sephadex LH-20 chromatography. IR, UV, MS, 1H, 13 CNMR, 1H- 1H COSY, 1H- 13 C COSY and HMBC spectra were used to determine the structure of the isolated constituents. RESULTS A new compound named quercetin 3′-methoxy-4′- O -β- D -glucopyranoside(I), together with three known compounds kaempferol(II), quercetin 4′- O -β- D -glucopyranoside(III) and quercetin 3,4′-di- O -β- D -glucopyranoside(IV) were isolated. CONCLUSION Quercetin 3′-methoxy-4′- O -β- D -glucopyranoside(I) is a new compound, compounds II～IV were isolated from this plant for the first time.

关 键 词：百合科 分蘖葱头 黄酮苷 分蘖葱头苷甲 

分 类 号：Q949.718.2[生物学—植物学]