蛋白质组学在中药研究中的应用  

Proteomics in study of traditional Chinese medicine

作　　者：李敏[1] 姜鹏[2] 王淑萍[2] 韩琳[2] 黄慧梅[1] 畅婉琳[1] 柳润辉[2] 

机构地区：[1]福建中医药大学药学院,福建福州350108 [2]第二军医大学药学院,上海200433

出　　处：《药学实践杂志》2013年第4期241-245,共5页Journal of Pharmaceutical Practice

摘　　要：系统生物学着眼于系统组成成分的构成、动态与发生,与中药对机体的整体而又动态的调节相符合,它的出现给中药研究带来了曙光。作为系统生物学的重要组成部分,蛋白质组学在中药研究中的应用已经越来越多。本文综述了蛋白质组学的常用技术以及近三年来这些技术在中药复方、中药有效部位和中药活性成分等方面的应用。Systems biology focused on constitute dynamic and development of system components, which was consistent with traditional Chinese medicine as a whole and dynamic adjustment to the body, It brought the dawn to reveal the mystery of TCM. As an important part of systems biology, proteomics had been more and more used in Chinese medicine research. The application of pro- teomics technologies in traditionol Chinese medicine and its effective parts and active ingredients in nearly three years were reviewed in this paper.

关 键 词：蛋白质组学 中药 二维凝胶电泳 差异凝胶电泳 同位素标记亲和标签 同位素标记相对和绝对定量技术 

分 类 号：TQ93[化学工程]