黄芪药材不同极性部位的指纹图谱  

Chromatographic fingerprints of diferent polarities from Radix Astragali

作　　者：刘小花[1] 白仲梅[2] 梁瑾[1] 封士兰[1] 

机构地区：[1]兰州大学药学院,兰州730000 [2]靖远煤业集团有限责任公司总医院药剂科,甘肃白银730913

出　　处：《兰州大学学报（自然科学版）》2013年第4期573-580,共8页Journal of Lanzhou University(Natural Sciences)

基　　金：中央高校基本科研业务费专项资金项目(lzujbky-2013-198);甘肃省中药药理与毒理学重点实验室开放基金项目(ZDSYS-KJ-2012-007);兰州市科技计划项目(2011-1-133)

摘　　要：对黄芪药材不同极性部位进行指纹图谱对比研究.采用HPLC法分别对10批黄芪药材的5个提取部位研究,流动相乙腈水溶液梯度洗脱.建立10批不同产地黄芪中5种极性部位的模式指纹图谱.首次鉴别7个主要指标成分.方法准确可靠,为全面控制药材质量提供了一种方法.The chromatographic fingerprints of different polarities from Radix Astragali and five extracts from 10 batches of Radix Astragali were studied. The mobile phase underwent ACN and H2O, gradient elution and the mode was established for the fingerprints of the five extracts from the 10 batches of Radix Astragali and seven main index components were identified for the first time. The method was accurate and reliable and the study may contribute to the quality control of Radix Astragali.

关 键 词：高效液相色谱 指纹图谱 质量控制 黄芪 

分 类 号：Q819[生物学—生物工程]