哨点监测人群中人类免疫缺陷病毒、梅毒、丙肝病毒感染的检测结果分析  

Sentinel surveillance of HIV,hepatitis C and syphilis infections

作　　者：汤琰[1] 孙乔[1] 顾春华[1] 张鹏[1] 张枭[1] 宋爱红[1] 

机构地区：[1]上海市浦东新区疾病预防控制中心,上海200136

出　　处：《诊断学理论与实践》2013年第3期352-354,共3页Journal of Diagnostics Concepts & Practice

基　　金：上海市浦东新区卫生系统重点学科建设资助(PWZXK2010-09)

摘　　要：目的:分析暗娼(FSW)、性病门诊男性就诊者(STD)、孕产妇(PRG)人群的艾滋病病毒(HIV)、丙肝病毒(HCV)、梅毒螺旋体(TP)感染流行趋势,为传染病的综合防治和干预提供科学依据。方法:在规定时间内,以重复横断面连续抽样的方法对FSW、STD、PRG人群进行哨点监测,由艾滋病性病实验室对其进行HIV、TP、HCV抗体检测。结果:2010年至2012年期间,STD人群的HIV感染率最高,为2.75‰,与FSW、PRG人群间差异均有统计学意义(χ2STD-FSW=7.913、χ2STD-PRG=6.512,P均<0.05);PRG人群的HCV感染率最低,为0.84‰,与FSW、STD人群间差异均有统计学意义(χ2PRG-STD=9.384、χ2PRG-FSW=8.272,P均<0.05)。各人群的TP-总感染率中,STD人群最高(22.18%),PRG人群最低(1.40%),两两间差异均有统计学意义(χ2STD-FSW=54.628、χ2STD-PRG=486.590、χ2FSW-PRG=395.208,P均<0.05);TP-现症感染率同样是STD人群最高(14.25%),PRG人群最低(0.38%),两两间差异亦有统计学意义(χ2STD-FSW=185.216、χ2STD-PRG=333.836、χ2FSW-PRG=87.501,P均<0.05)。结论:需进一步对FSW、STD、PRG人群完善监测措施,提高监测效果;同时应加强性安全教育宣传,从源头上降低TP和HIV的感染率。Objective： To analyze the prevalence of HIV , hepatitis C virus （HCV） and Treponema pallidum （TP） infections in female sex workers （FSW） , male sexual transmitted disease patients（STD）, and pregnant women （PRG）groups under sentinel surveillance, and to provide evidences for prevention and intervention. Methods： In sentinel surveillance FSW, STD, PRG groups were monitored by repeated cross-sectional sampling within the time scheduled, and Anti-HIV, Anti-TP, Anti HCV were detected by an AIDS STD Laboratory. Results： During 2010-2012, the HIV infection rate in STD group was the highest （2.75%o）, and significant difference was found when compared with the other two groups （X2sv^sw=7.913 ~XZS-~_pR~;=6.512,P〈O.05）. HCV infection rate was the lowest （0.84%~） in PRG group, lower than the other two groups （X2PRC_SVD=9.384,X2e^C~FSW=8.272 ,P〈O.05）. The STD group had the highest overall TP infection rate （22.18%）, and the lowest rate（1.40%） was seen in PRG group. Significant difference was found between mutual groups （X2smvsw=54.628, X2s＇ro-pRG=486.590,X2rs^-~C=395.208,P〈O.05）. TP-novel infection rate in STD group was the highest （14.25%）, and the lowest rate was seen in PRG group （0.38%）, and significant difference was found between mutual groups （X2sqrsw= 185.216,X2sTPRO=333.836 ,X2rSW_PRG=87-501 ,P〈0.05）. Conclusions： Further monitoring of HIV, hepatitis C and syphilis in FSW, STD, PRG groups is needed. Meanwhile, safe sex education to the public should be strengthened for lowering the infection rate of TP and HIV.

关 键 词：艾滋病 丙肝 梅毒 监测 

分 类 号：R512.91[医药卫生—内科学]