四苯基卟啉及其衍生物的合成  

Synthesis of Tetraphenylporphyrin and Its Derivatives

作　　者：吴平[1] 丁元生[1] 史晋宜[1] 刘治刚[1] 陈霄[1] 娄大伟[1] 

机构地区：[1]吉林化工学院,化学与制药工程学院,吉林吉林132022

出　　处：《化学世界》2013年第9期535-537,共3页Chemical World

基　　金：吉林省科学技术厅科技发展计划项目(20101547;20110345)

摘　　要：以吡咯为起始原料,在丙酸的催化下,与苯甲醛缩合成四苯基卟啉;用质量分数为65%的浓硝酸选择性单硝化TPP,并用氯化亚锡还原得氨基化TPP。结果表明:采用丙酸催化,反应2.0h,四苯基卟啉产率为24.6%,单硝化TPP产率为54.1%,还原TPP产率为46.1%。该反应合成路线和具体实验条件对相关化合物的合成具有较好的借鉴意义。Pyrrole and benzaldehyde＇s derivatives were reacted in propionic acid to prepare tetraphenylpor- phyrin （TPP）. The mono nitro TPP was obtained through the reaction of 65%concentrated nitric acid and TPP, and then it was reduced by tin（Ⅱ）chloride： The yield of TPP reached about 24.6%, mono nitro TPP reached 54.1% ,and the reduction product reached 46.1%. The reaction route and conditions will give useful guide to synthesis of relative compounds.

关 键 词：四苯基卟啉衍生物 硝化 还原 

分 类 号：O625.65[理学—有机化学]