急性心肌梗死与血清尿酸、同型半胱氨酸和血浆纤维蛋白原的相关性研究  

Correlation study of acute myocardial infarction and serum uric acid,homocysteine and plasma fibrinogen

作　　者：姜昌丽[1] 余政礼 贾雄飞[1] 滕毅[1] 毕再华[1] 李艳姣[1] 王惠萱[1] 

机构地区：[1]成都军区昆明总医院检验科,云南昆明650032 [2]昆明医科大学,2008级检验专业云南昆明650223

出　　处：《国际检验医学杂志》2013年第17期2211-2211,2215,共2页International Journal of Laboratory Medicine

基　　金：国家高技术研究发展计划(863计划)<体外诊断技术产品开发重大项目>"心脑血管慢性损伤及急救指标等体外诊断试剂的研制"子课题"血浆Hcy与肾透析患者的关系研究"(2011AA02A111)

摘　　要：目的探讨急性心肌梗死(AMI)与血清尿酸(UA)、同型半胱氨酸(Hcy)、血浆纤维蛋白原(FIB)的相关性,为早期预防AMI提供重要的实验室依据。方法选取177例已经确诊为AMI的患者,检测UA、Hcy和FIB水平,并与197例对照组进行比较,分析各项指标之间的相关性。结果 AMI组UA、Hcy和FIB水平显著高于对照组,差异有统计学意义(P<0.01)。结论UA、Hcy和FIB的联合检测为AMI的早期预防提供重要的参考价值。Objective To provide important laboratory evidence for early prevention of acute myocardial infarction by exploring the correlation study of acute myocardial infarction（AMI）and serum uric acid（UA）,homocysteine（Hcy）,and plasma fibrinogen（FIB）.Methods Serum UA,serum Hcy and plasma FIB of 177patients with AMI and 197cases of controls were determined respectively.The test results were analyzed statistically.Results The UA,Hcy and FIB of ABI group were significantly higher than the control group.The differences were statistically significant（P0.01）.Conclusion UA,Hcy and FIB combined detection can provide an important reference value for early prevention of AMI.

关 键 词：急性心肌梗死 尿酸 半胱氨酸 纤维蛋白原 

分 类 号：R542.22[医药卫生—心血管疾病]