老年细菌性肺炎的病原菌分布特点及耐药性分析  

Pathogenic bacteria of senile pneumonia and their drug resistance

作　　者：李代昆[1] 陈庆海[1] 府伟灵[1] 张德纯[2] 

机构地区：[1]第三军医大学西南医院检验科,重庆400038 [2]重庆医科大学检验系,重庆400016

出　　处：《国际检验医学杂志》2013年第17期2234-2237,2240,共5页International Journal of Laboratory Medicine

摘　　要：目的分析老年细菌性肺炎的病原菌分布特点及耐药性,了解该地流行菌株的分布及耐药状况,为临床医师合理使用抗菌药物提供参考依据。方法对老年细菌性肺炎患者的痰液进行常规细菌培养鉴定,用K-B法进行药物敏感试验并统计分析。结果老年人因体质虚弱和基础疾病易患细菌性肺炎,主要病原菌为肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌、鲍曼不动杆菌和金黄色葡萄球菌,均呈现严重的耐药性,可能与抗生素大量使用有关。结论严格掌握抗生素的应用指征,用药前进行细菌分离鉴定和药敏试验,以保证临床合理用药,遏止细菌耐药性快速增长的不良趋势。Objective To analyse the distribution and antimicrobial resistance of pathogenic bacteria in senile patients with pneumonia in order to provide the reference for reasonable clinical use of antibiotics.Methods The sputum of senile patients with bacterial infectious pneumonia were cultured to detect pathogens by routine methods.The drug susceptibility test was performed by K-B method and its results were analyzed.Results Senile patients were prone to be infected by bacterial pneumonia because of their poor health and basic diseases.The major pathogenic bacteria were Klebsiella pneumoniae,Escherichia coli,Pseudomonas aeruginosa,Acinetobacter baumannii,and Staphylococcus aureus and their drug susceptivity was poor for major antibiotics because of the abuse of antibiotics year by year.Conclusion Bacteria culture,identification and drug susceptivity test are needed before a prescription for antibiotics to guarantee the reasonable use of antibiotics.

关 键 词：肺炎 老年 病原 细菌 微生物敏感试验 

分 类 号：R446.5[医药卫生—诊断学]