以钼磷酸为催化剂合成妊娠双烯醇酮醋酸酯研究  

Study on Synthetic 16-Dehydropregnenolone Acetate Catalyzed by Molybdophosphate Acid

作　　者：季晓晖[1] 

机构地区：[1]陕西理工学院,陕西汉中723000

出　　处：《广东化工》2013年第17期33-34,共2页Guangdong Chemical Industry

基　　金：陕西省科技厅"13115工程中心"项目"妊娠双烯醇酮醋酸酯绿色合成工艺研究(2010ZDGC-23-14)"

摘　　要：以薯蓣皂素为原料,30%H2O2为氧化剂,硅胶固载的钼磷酸为催化剂,对合成妊娠双烯醇酮醋酸酯进行了初步研究。利用熔点测定法、红外光谱高和效液相色谱对双烯产品进行定性鉴定。结果表明:妊娠双烯醇酮醋酸酯总收率为38%。The oxidation reactions in the synthetic process of 16-dehydropregnenolone acetate from diosgenin was preliminary studied, which using 30 % H2O2 as oxidant, phosphorus molybdenum acid supported on silica gel as catalyst. Instrumental Methods, namely Melting Point Testing, IR and HPLC, instead of chemical analysis methods are applied for qualitative identification of solid samples containing the product 16-dehydropregnenolone. The results showed： the The total yield of 16-dehydropregnenolone acetate was 38 %.

关 键 词：薯蓣皂素 妊娠双烯 钼磷酸 

分 类 号：TQ[化学工程]