原发性胆汁性肝硬化中医证候分型文献分析  

A literature retrieval o n classification and characteristics of traditional Chinese medicine syndromes in patients with primary biliary cirrhosis

作　　者：张宁[1] 宫嫚[1] 周双男[2] 冯松[3] 孙永强[1] 景婧[1] 杜宁[1] 张帆[1] 罗生强[1] 

机构地区：[1]解放军第302医院中西医结合肝病诊疗与研究中心,北京市100039 [2]北京市解放军第302医院肝脏移植内科,100039 [3]北京市解放军第302医院医学影像中心,100039

出　　处：《实用肝脏病杂志》2013年第5期445-447,共3页Journal of Practical Hepatology

摘　　要：目的了解现有原发性胆汁性肝硬化临床研究文献中中医证候规律的特点。方法检索中国期刊全文数据库、万方数据库和维普数据库,收集并阅读全文,筛选出符合纳入标准的文献,提取证候类型和辨证依据等资料,进行描述性统计学分析。结果在检索出的78篇文献中,符合纳入条件的文献7篇,所涉及原发性胆汁性肝硬化中医证型共20种,排名在前6位的中医证型分别为:肝郁脾虚(34.85%)、肝肾阴虚(27.82%)、湿热瘀血(6.69%)、湿热蕴结(4.23%)、脾胃气虚(3.87%)和湿滞血瘀(3.52%);证候分型要素共14个,排名前6位的分别为脾虚(40.49%)、肝郁(39.43%)、肝阴虚(31.34%)、肾阴虚(31.34%)、瘀血(25.70%)和湿热(17.25%)。结论中医研究原发性胆汁性肝硬化的论文水平较低,分型依据缺乏科学性。Objective To investigate the classification and characteristics of traditional Chinese Medicine （TCM）syndromes in patients with primary biliary cirrhosis （PBC）in Chinese literatures. Methods Chinese litera-tures on primary biliary cirrhosis were retrieving from CNKI database,Wanfang database and Chongqing VIP database. Eligible literatures were then reviewed. Results Seven papers were included in this study. A total of 20 types of TCM syndromes about PBC were found in these papers,and the common types were liver stagnation and spleen deficiency （34.85%）,liver-and kidney-Yin deficiency （27.82%）,damp heat and blood stasis （6.69%）, damp and hot accumulate knot（4.23%）,spleen- and stomach-qi deficiency（3.87%）,dampness stagnation and blood stasis （3.52%）;Fourteen elements based on which the TCM syndrome were determined involved spleen deficien-cy（40.49%）,liver stagnation （39.43%）,liver-Yin deficiency（31.34%）,kidney-Yin deficiency（31.34%）,blood stasis （25.70%）and heat and humidity（17.25%）. Conclusion We do not recommend the sophisticated TCM syndromes for PBC study at the time as they just are diagnosed by subjective features.

关 键 词：原发性胆汁性肝硬化 中医证候 文献分析 

分 类 号：R259[医药卫生—中西医结合]