脾切除对几种血液病的治疗作用(附56例分析)  

Splenectomy for some hematologic diseases

作　　者：石欣[1] 吴涛[2] 嵇振岭[1] 高乃荣[1] 刘训钰[1] 陈怀仁[1] 

机构地区：[1]南京铁道医学院附属医院普外科,南京210009 [2]济南铁路中心医院外二科

出　　处：《中华肝胆外科杂志》2000年第5期349-351,共3页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的　总结对血液病病人行脾切除的治疗效果、适应证和手术并发症。方法　回顾性分析 1981～ 1998年间 5 6例血液病病人脾切除术的资料 ,根据治疗效果 ,总结出适应证及并发症的预防。结果　根据血液学参数结果 ,脾切除对原发性血小板减少性紫癜、遗传性球形红细胞增多症、自身免疫性溶血性贫血、原发性血小板减少性紫癜合并自身免疫性溶血性贫血 (Evans病 )有确切的治疗效果 ,有效率分别为 87 5 % ,80 % ,77 8%和 6 6 7%。结论　脾切除对上述疾病行之有效。合理应用激素并不增加术后感染率 ,围手术期内不需要长期应用抗生素。Objective To investigate the therapeutic efficacy, indications and complications of splenectomy performed in patients suffering from hematological diseases. Methods From 1981 to 1998, 56 patients suffering from hematological diseases underwent splenectomy in our hospital. We summed up the indications, ideal operational opportunity and the ways of preventing the complications. Results Determination of postoperative hematological parameters indicated that splenectomy could exert significant therapeutic effects on the diseases of idiopathic thrombocytopenic purpura (ITP), hereditary spherocytosis (HS), autoimmune hemolytic anemia (AHA) and Evans syndrome. The effective rates were 87.5%, 80.0%, 77.8% and 66.7%, respectively. Conclusions Splenectomy is effective for treatment of some hematological diseases. Reasonable use of hormone does not result in increase postoperative infections. It is unnecessary to use antibiotics for a long time after the operation.

关 键 词：血液病 脾切除术 适应证 并发症 

分 类 号：R657.6[医药卫生—外科学]