葡萄糖酸铬对糖尿病小鼠血糖水平的影响  

Effects of Chromium gluconate on Blood sugar of Diabetic Mice

作　　者：文香兰[1] 李善花[1] 王启伟[1] 金英锦[1] 文永植[1] 张啺 张宏绪[2] 

机构地区：[1]延边大学医学院,延吉133000 [2]哈尔滨医科大学公共卫生学院,哈尔滨150001

出　　处：《微量元素与健康研究》2000年第4期1-2,共2页Studies of Trace Elements and Health

摘　　要：用葡萄糖氧化酶法观察了口服葡萄糖酸铬 1 0 μg/kg体重·每日及 5μg/kg体重·每日 ,连续 2 8天的四氧嘧啶所致糖尿病小鼠血糖水平。结果 :每日 1 0μg/kg体重组血糖与实验前及糖尿病对照组比较均有明显下降 ,差异极其显著 (P<0 .0 1 ) ;每日 5μg/kg体重比实验前有所下降 (0 .0 1 <P<0 .0 5) ,但与糖尿病对照组比较无显著性 (P>0 .0 5)With the method of GOD-PAP,the effect of Chromium Giuconate (10.5 μg/kg d)on blood sugar of diabetic mice induced by alloxan was observed,by oral administration for 28 days.It was showed that the blood sugar had a significant decreasing in the 10 μg/kg.d group,compared to before experiment and diabetic control (P<0.01);it had a decreasing in the 5 μg/kg.d,compared to before experiment (0.01<P<0.05);but compared to diabetic control,no significance P>0.05).

关 键 词：铬 糖尿病 血糖 小鼠 

分 类 号：R587.2[医药卫生—内分泌]