甲状腺机能亢进症患者部分骨代谢生化指标的变化及分析  

Determination of partial biochemical markers of bone metabolism in patients with hyperthyroidism

作　　者：孙玉倩[1] 高萍[1] 李强[1] 张巾超[1] 

机构地区：[1]哈尔滨医科大学第二临床医学院,黑龙江哈尔滨150086

出　　处：《中国地方病学杂志》2000年第6期409-410,共2页Chinese Jouranl of Endemiology

摘　　要：目的　查明甲状腺机能亢进症患者血清骨钙素 (BGP)、碱性磷酸酶 (AL P)及尿羟脯氨酸 (HOP) ,观察其变化并进行分析。方法　以 30例甲亢患者及 15例正常人为研究对象 ,测定 BGP、AL P、尿 HOP等指标。结果　甲亢患者血清 BGP(11.18± 4.74) ng/ m l和尿 HOP(2 4.32± 11.2 1) mg/ g.Cr均高于正常对照组 (P <0 .0 5)。Objective To observe and analyse the changes of partial biochemical markers in patients with hyperthyroidism.Methods We determinate the levels of BGP,ALP,HOP in 30 patients with hyperthyroidism and 15 normal subjects.Results The levels of serum BGP (11.18±4.74) ng/ml andurine HOP (24.32±11.21) mg/g.Cr in hyperthyroid group were higher than those in the control one.Conclusions The increasing of bone resorption and the relative decreasing of bone formation might lead to abnormal bone metabolism in hyperthyroidism.

关 键 词：甲状腺机能亢进 骨代谢 骨钙素 尿羟脯氨酸 

分 类 号：R581.106[医药卫生—内分泌] R681.02[医药卫生—内科学]