邻苯二甲酸二（2-乙基己）酯对儿童发育及代谢的影响  

Effects of Di （2-ethylhexyl） phthalate on development and metabolism in children

作　　者：赵青松[1] 吴德(综述)[1] 都鹏飞(审校)[2] 

机构地区：[1]安徽医科大学第一附属医院儿科,合肥230022 [2]安徽医科大学第二附属医院儿科,合肥230601

出　　处：《国际儿科学杂志》2013年第5期511-513,共3页International Journal of Pediatrics

摘　　要：随着现代科技的发展，越来越多的塑料制品被广泛应用于各种领域，给社会带来便利的同时，也导致环境雌激素越来越多。“塑化剂”的影响越来越大，尤其是对发育的儿童，广泛接触塑化剂，被认为与儿童性腺发育异常、肥胖等密切相关。该文重点综述邻苯二甲酸二（2-乙基己）酯的基础研究及临床最新研究结果，探讨阐明邻苯二甲酸二（2-乙基己）酯对儿童发育及代谢的影响，为临床合理干预和科学使用塑化剂奠定基础。With the development of modem technology, more and more plastic products are widely used in various fields, while bringing significant convenience to the society, it also leads to more and more environ- mental estrogen. The influence of ＂plasticizer＂ is increasing, especially on the development of children. Exten- sive contacting with plasticizer is considered to be closely related with gonadal digenesis, obesity and other prob- lems in children. This review focuses on the latest research results about the basic and clinical experiments of Di （2-ethylhexyl） phthalate （DEHP）, which illuminate the effects of DEHP on children＇s growth and metabolism, and lay foundations for rational clinical intervention and scientific plasticizer＇s application.

关 键 词：邻苯二甲酸二（2-乙基己）酯 塑化剂 代谢 循环 

分 类 号：R114[医药卫生—卫生毒理学]