宁夏回族人群定量CT骨密度研究  

Study of bone mineral density with quantitative CT in Ningxia Hui people.

作　　者：雷晨[1] 赵芸芸[2] 张婕[2] 李美娟[2] 李伟[2] 夏玲玲[2] 

机构地区：[1]宁夏医科大学总医院内分泌科,宁夏银川750004 [2]宁夏医科大学临床医学院,宁夏银川750004

出　　处：《海南医学》2013年第17期2512-2514,共3页Hainan Medical Journal

基　　金：宁夏银川市2010年科技攻关项目

摘　　要：目的研究宁夏地区不同年龄、不同性别回族人群骨密度随年龄变化的规律及差异性。方法收集2011年7～12月宁夏地区回族经双能X线吸收测定仪证实为正常的人群（男性181名、女性231名）进行定量CT检查，同时填写一般状况调查表。结果（1）选8名志愿者，对L2-4椎体测定3次骨密度值，进行定量CT值校正，变异系数分别为1．82％、1．91％、1．87％。（2）回族男性出现骨峰值的年龄段为30-33．8岁，平均（31．1±1．2）岁；女性出现骨峰值的年龄段为29．8±35．1岁，平均（30．7±2．6）岁。随年龄增大，回族男性在峰值过后骨密度均逐渐下降，女性在峰值过后骨密度呈现逐渐下降。在（43．9±2．7）岁后，回族女性骨量丢失明显增快。（3）回族人群的骨密度与行业、体重、饮食习惯、停经年龄等密切相关，而与运动状况、吸烟和饮酒无明确的相关性。结论定量CT充分利用CT断层解剖定位的特点，能在三维立体空间上区分松质骨和皮质骨，选择性测量松质骨能排除皮质骨的增生硬化和邻近组织对测量的影响，对诊断骨质疏松有较高的敏感性和特异性。回族人群中女性在（43．9±2．7）岁以后出现明显的骨量降低，而宁夏地区男性未表现出明显的骨量降低，考虑主要与其测量人员中的年龄较轻有关。Objective To investigate the changes and differences of bone mineral density in Ningxia Ningxia Hui people under different age and gender. Methods A total of 181 males and 231 females from Ningxia Hui people who were confirmed normal by dual-energy X-ray absorptiometry from July 2011 to December 2011 were collected. The subjects all underwent quantitative CT and completed the questionnaire regarding the general condition. Results （1） Bone mineral density of eight volunteers was measured for three times in L2-4 lumbar verte- bral body. The quantitative CT values were corrected, and the variation coefficients were 1.82%, 1.91%, 1.87%. （2） The males showed peak bone mineral density from 30 to 33.8 years old, （31.1±1.2） years old in average; The females showed peak bone mineral density from 29.8 to 35.1 years old, （30.7±2.6） years old in average. With the increase of age, the bone mineral density of males was decreased gradually after the peak. The bone mineral density of females de- creased gradually after the peak and decreased significantly after （43.9±2.7） years old. （3） The bone mineral density of Ningxia Hui people were closely related to the industry, weight, eating habits, the age of menopause, and showed no significant correlation with the exercise status, smoking or drinking. Conelusion The quantitative CT makes full use of the features of CT anatomical localization, and can distinguish the cancellous bone and cortical bone in three-dimen- sional space, selective measure the cancellous bone and exclude the effect of the measurement of the cortical bone sclerosis and adjacent tissue, with high sensitivity and specificity. The female Ningxia Hui people shows significant de- crease in bone mineral density after （43.9±2.7） years old, while the males have no significant decrease, which might due to the age of the subjects.

关 键 词：宁夏 回族人群 定量CT 骨密度 

分 类 号：R322.71[医药卫生—人体解剖和组织胚胎学]